Privacy in the age of computers and a Nature reader questions eyewitness accounts of boomerangs in our weekly dip into the archive.]]>
+
+
+ doi:10.1038/d41586-025-03989-3
+ Nature, Published online: 2025-12-30; | doi:10.1038/d41586-025-03989-3
+ 2025-12-30
+ Nature
+ 10.1038/d41586-025-03989-3
+ https://www.nature.com/articles/d41586-025-03989-3
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04026-z
+
+ Nature, Published online: 30 December 2025; doi:10.1038/d41586-025-04026-zConstructive feedback.]]>
+
+ Dawn Vogel
+ doi:10.1038/d41586-025-04026-z
+ Nature, Published online: 2025-12-30; | doi:10.1038/d41586-025-04026-z
+ 2025-12-30
+ Nature
+ 10.1038/d41586-025-04026-z
+ https://www.nature.com/articles/d41586-025-04026-z
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04100-6
+
+ Nature, Published online: 30 December 2025; doi:10.1038/d41586-025-04100-6Nuclear fusion. People on Mars. Artificial general intelligence. These are just some of the advances that could come by the mid-century mark.]]>
+
+ David Adam
+ doi:10.1038/d41586-025-04100-6
+ Nature, Published online: 2025-12-30; | doi:10.1038/d41586-025-04100-6
+ 2025-12-30
+ Nature
+ 10.1038/d41586-025-04100-6
+ https://www.nature.com/articles/d41586-025-04100-6
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04103-3
+
+ Nature, Published online: 30 December 2025; doi:10.1038/d41586-025-04103-3A challenging exhibition asks why we are so fascinated with the preserved bodies of our ancestors, and how we should treat them.]]>
+
+ Laura Spinney
+ doi:10.1038/d41586-025-04103-3
+ Nature, Published online: 2025-12-30; | doi:10.1038/d41586-025-04103-3
+ 2025-12-30
+ Nature
+ 10.1038/d41586-025-04103-3
+ https://www.nature.com/articles/d41586-025-04103-3
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04099-w
+
+ Nature, Published online: 30 December 2025; doi:10.1038/d41586-025-04099-wJournals that work hard to meet the needs of both authors and readers should be acknowledged publicly — encouraging others to follow suit.]]>
+
+ Jennifer A. Byrne
+ doi:10.1038/d41586-025-04099-w
+ Nature, Published online: 2025-12-30; | doi:10.1038/d41586-025-04099-w
+ 2025-12-30
+ Nature
+ 10.1038/d41586-025-04099-w
+ https://www.nature.com/articles/d41586-025-04099-w
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04147-5
+
+ Nature, Published online: 29 December 2025; doi:10.1038/d41586-025-04147-5Researchers are investigating whether GLP-1 drugs can help blunt cravings for nicotine, alcohol and opioids.]]>
+
+ Elie DolginBenjamin Thompson
+ doi:10.1038/d41586-025-04147-5
+ Nature, Published online: 2025-12-29; | doi:10.1038/d41586-025-04147-5
+ 2025-12-29
+ Nature
+ 10.1038/d41586-025-04147-5
+ https://www.nature.com/articles/d41586-025-04147-5
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04105-1
+
+ Nature, Published online: 29 December 2025; doi:10.1038/d41586-025-04105-1Buse Tuğba Zaman is developing a way to track tiny amounts of contaminants — and fulfilled a dream to visit Earth’s most remote continent.]]>
+
+ Rachael Pells
+ doi:10.1038/d41586-025-04105-1
+ Nature, Published online: 2025-12-29; | doi:10.1038/d41586-025-04105-1
+ 2025-12-29
+ Nature
+ 10.1038/d41586-025-04105-1
+ https://www.nature.com/articles/d41586-025-04105-1
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04104-2
+
+ Nature, Published online: 29 December 2025; doi:10.1038/d41586-025-04104-2Encouraging academics to act as advisers to outside organizations is the most effective way to serve society’s needs.]]>
+
+ Louise J. SlaterWeston B. StruweChristopher R. VogelEmma WalkerRegent Lee
+ doi:10.1038/d41586-025-04104-2
+ Nature, Published online: 2025-12-29; | doi:10.1038/d41586-025-04104-2
+ 2025-12-29
+ Nature
+ 10.1038/d41586-025-04104-2
+ https://www.nature.com/articles/d41586-025-04104-2
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04106-0
+
+ Nature, Published online: 29 December 2025; doi:10.1038/d41586-025-04106-0AI technologies need to be safe and transparent. There are few, if any, benefits from being outside efforts to achieve this.]]>
+
+
+ doi:10.1038/d41586-025-04106-0
+ Nature, Published online: 2025-12-29; | doi:10.1038/d41586-025-04106-0
+ 2025-12-29
+ Nature
+ 10.1038/d41586-025-04106-0
+ https://www.nature.com/articles/d41586-025-04106-0
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04101-5
+
+ Nature, Published online: 29 December 2025; doi:10.1038/d41586-025-04101-5If you’ve hatched a New Year plan to move abroad, improve your presentations or chase happiness as a 20-something researcher, you’ll find advice aplenty in these books.]]>
+
+ Anne Gulland
+ doi:10.1038/d41586-025-04101-5
+ Nature, Published online: 2025-12-29; | doi:10.1038/d41586-025-04101-5
+ 2025-12-29
+ Nature
+ 10.1038/d41586-025-04101-5
+ https://www.nature.com/articles/d41586-025-04101-5
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03756-4
+
+ Nature, Published online: 24 December 2025; doi:10.1038/d41586-025-03756-4The team select some of their favourite stories from the past 12 months.]]>
+
+ Benjamin ThompsonNick Petrić HoweElizabeth GibneyDan FoxShamini Bundell
+ doi:10.1038/d41586-025-03756-4
+ Nature, Published online: 2025-12-24; | doi:10.1038/d41586-025-03756-4
+ 2025-12-24
+ Nature
+ 10.1038/d41586-025-03756-4
+ https://www.nature.com/articles/d41586-025-03756-4
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10044-8
+
+ Nature, Published online: 23 December 2025; doi:10.1038/s41586-025-10044-8Author Correction: Rolling back human pluripotent stem cells to an eight-cell embryo-like stage]]>
+
+ Md. Abdul MazidCarl WardZhiwei LuoChuanyu LiuYunpan LiYiwei LaiLiang WuJinxiu LiWenqi JiaYu JiangHao LiuLixin FuYueli YangDavid P. IbañezJunjian LaiXiaoyu WeiJuan AnPengcheng GuoYue YuanQiuting DengYang WangYing LiuFei GaoJunwen WangShahriar ZamanBaoming QinGuangming WuPatrick H. MaxwellXun XuLongqi LiuWenjuan LiMiguel A. Esteban
+ doi:10.1038/s41586-025-10044-8
+ Nature, Published online: 2025-12-23; | doi:10.1038/s41586-025-10044-8
+ 2025-12-23
+ Nature
+ 10.1038/s41586-025-10044-8
+ https://www.nature.com/articles/s41586-025-10044-8
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04068-3
+
+ Nature, Published online: 23 December 2025; doi:10.1038/d41586-025-04068-3Vernon Morris inspires change in the geoscience community by calling on colleagues to commit to anti-racism in their scientific endeavours.]]>
+
+ Rachel Crowell
+ doi:10.1038/d41586-025-04068-3
+ Nature, Published online: 2025-12-23; | doi:10.1038/d41586-025-04068-3
+ 2025-12-23
+ Nature
+ 10.1038/d41586-025-04068-3
+ https://www.nature.com/articles/d41586-025-04068-3
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10058-2
+
+ Nature, Published online: 22 December 2025; doi:10.1038/s41586-025-10058-2NAC controls nascent chain fate through tunnel sensing and chaperone action]]>
+
+ Jae Ho LeeLaurenz RablMartin GamerdingerVaishali GoyalKatrin Michaela KhakzarNatalia Moreira BarbosaJuliana AbramovichFabian Morales-PolancoAnn-Kathrin KöhlerEkaterina SamatovaMarina V. RodninaElke DeuerlingJudith Frydman
+ doi:10.1038/s41586-025-10058-2
+ Nature, Published online: 2025-12-22; | doi:10.1038/s41586-025-10058-2
+ 2025-12-22
+ Nature
+ 10.1038/s41586-025-10058-2
+ https://www.nature.com/articles/s41586-025-10058-2
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10056-4
+
+ Nature, Published online: 22 December 2025; doi:10.1038/s41586-025-10056-4Non-equilibrium snapshots of ligand efficacy at the μ-opioid receptor]]>
+
+ Michael J. RobertsonArnab ModakMakaía M. Papasergi-ScottMiaohui HuMaria Claudia PerotoBalazs R. VargaSusruta MajumdarRavi KalathurScott C. BlanchardGeorgios Skiniotis
+ doi:10.1038/s41586-025-10056-4
+ Nature, Published online: 2025-12-22; | doi:10.1038/s41586-025-10056-4
+ 2025-12-22
+ Nature
+ 10.1038/s41586-025-10056-4
+ https://www.nature.com/articles/s41586-025-10056-4
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04120-2
+
+ Nature, Published online: 22 December 2025; doi:10.1038/d41586-025-04120-2Can you spot the penguin in every game this year?]]>
+
+ Flora GrahamJacob Smith
+ doi:10.1038/d41586-025-04120-2
+ Nature, Published online: 2025-12-22; | doi:10.1038/d41586-025-04120-2
+ 2025-12-22
+ Nature
+ 10.1038/d41586-025-04120-2
+ https://www.nature.com/articles/d41586-025-04120-2
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10022-0
+
+ Nature, Published online: 19 December 2025; doi:10.1038/s41586-025-10022-0Author Correction: Cryo-EM structure of a natural RNA nanocage]]>
+
+ Xiaobin LingDmitrij GolovenkoJianhua GanJinbiao MaAndrei A. KorostelevWenwen Fang
+ doi:10.1038/s41586-025-10022-0
+ Nature, Published online: 2025-12-19; | doi:10.1038/s41586-025-10022-0
+ 2025-12-19
+ Nature
+ 10.1038/s41586-025-10022-0
+ https://www.nature.com/articles/s41586-025-10022-0
+
+
+
+ Nature's News & Views roundup of 2025]]>
+ https://www.nature.com/articles/d41586-025-04065-6
+
+ Nature, Published online: 19 December 2025; doi:10.1038/d41586-025-04065-6From astrophysics to genetics, climate change to materials science — the News & Views team talk about some of their science highlights of 2025.]]>
+ Nature's News & Views roundup of 2025]]>
+ Benjamin ThompsonAndrew MitchinsonHolly Smith
+ doi:10.1038/d41586-025-04065-6
+ Nature, Published online: 2025-12-19; | doi:10.1038/d41586-025-04065-6
+ 2025-12-19
+ Nature
+ 10.1038/d41586-025-04065-6
+ https://www.nature.com/articles/d41586-025-04065-6
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04118-w
+
+ Nature, Published online: 19 December 2025; doi:10.1038/d41586-025-04118-wIt’s a mystery why TOI-561 b’s blanket of gases hasn’t boiled off.]]>
+
+
+ doi:10.1038/d41586-025-04118-w
+ Nature, Published online: 2025-12-19; | doi:10.1038/d41586-025-04118-w
+ 2025-12-19
+ Nature
+ 10.1038/d41586-025-04118-w
+ https://www.nature.com/articles/d41586-025-04118-w
+
+
+
+ Stranger Things]]>
+ https://www.nature.com/articles/d41586-025-04088-z
+
+ Nature, Published online: 19 December 2025; doi:10.1038/d41586-025-04088-zNature speaks to theoretical physicists to explore the real theories that inspired the hit series. Warning: contains spoilers.]]>
+ Stranger Things]]>
+ Jenna Ahart
+ doi:10.1038/d41586-025-04088-z
+ Nature, Published online: 2025-12-19; | doi:10.1038/d41586-025-04088-z
+ 2025-12-19
+ Nature
+ 10.1038/d41586-025-04088-z
+ https://www.nature.com/articles/d41586-025-04088-z
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04032-1
+
+ Nature, Published online: 19 December 2025; doi:10.1038/d41586-025-04032-1Tools fail to identify most AI-generated peer-review reports, say researchers, who warn that the issue is only getting worse.]]>
+
+ Dalmeet Singh Chawla
+ doi:10.1038/d41586-025-04032-1
+ Nature, Published online: 2025-12-19; | doi:10.1038/d41586-025-04032-1
+ 2025-12-19
+ Nature
+ 10.1038/d41586-025-04032-1
+ https://www.nature.com/articles/d41586-025-04032-1
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04108-y
+
+ Nature, Published online: 19 December 2025; doi:10.1038/d41586-025-04108-yThe US administration is banking on public–private partnerships and an expanded workforce to deliver progress, but critics say that this strategy could be offset by other US policies.]]>
+
+ Jenna Ahart
+ doi:10.1038/d41586-025-04108-y
+ Nature, Published online: 2025-12-19; | doi:10.1038/d41586-025-04108-y
+ 2025-12-19
+ Nature
+ 10.1038/d41586-025-04108-y
+ https://www.nature.com/articles/d41586-025-04108-y
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09982-0
+
+ Nature, Published online: 18 December 2025; doi:10.1038/s41586-025-09982-0Publisher Correction: Covalent targeted radioligands potentiate radionuclide therapy]]>
+
+ Xi-Yang CuiZhu LiZiren KongYu LiuHao MengZihao WenChanglun WangJunyi ChenMengxin XuYiyan LiJingyue GaoWenjia ZhuZhixin HaoLi HuoShaoyan LiuZhi YangZhibo Liu
+ doi:10.1038/s41586-025-09982-0
+ Nature, Published online: 2025-12-18; | doi:10.1038/s41586-025-09982-0
+ 2025-12-18
+ Nature
+ 10.1038/s41586-025-09982-0
+ https://www.nature.com/articles/s41586-025-09982-0
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04139-5
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-04139-5Andrew Robinson reviews five of the best science picks.]]>
+
+ Andrew Robinson
+ doi:10.1038/d41586-025-04139-5
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-04139-5
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-04139-5
+ https://www.nature.com/articles/d41586-025-04139-5
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04078-1
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-04078-1Some cycads warm up their reproductive organs to attract specially equipped pollinating beetles in the dark.]]>
+
+
+ doi:10.1038/d41586-025-04078-1
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-04078-1
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-04078-1
+ https://www.nature.com/articles/d41586-025-04078-1
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04107-z
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-04107-zThe COVID-19 pandemic, Ebola, mpox and AIDS all show the importance of strengthening Africa-wide surveillance and response systems that protect everyone.]]>
+
+ Paul Adepoju
+ doi:10.1038/d41586-025-04107-z
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-04107-z
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-04107-z
+ https://www.nature.com/articles/d41586-025-04107-z
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03673-6
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-03673-6The rise of AI scientists, missions to explore the moons of Earth and Mars and a massive ocean-floor drill are among the developments set to shape research in 2026.]]>
+
+ Miryam Naddaf
+ doi:10.1038/d41586-025-03673-6
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-03673-6
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-03673-6
+ https://www.nature.com/articles/d41586-025-03673-6
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04060-x
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-04060-xWith so little money to go round, the costs of competing for grants can exceed what the grants are worth. When that happens, nobody wins.]]>
+
+ Gerald Schweiger
+ doi:10.1038/d41586-025-04060-x
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-04060-x
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-04060-x
+ https://www.nature.com/articles/d41586-025-04060-x
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03810-1
+
+ Nature, Published online: 18 December 2025; doi:10.1038/d41586-025-03810-1Unexpected behaviours in G proteins could be exploited to design next-generation opioid drugs that provide stronger, longer-lasting pain relief.]]>
+
+ Andrew B. Tobin
+ doi:10.1038/d41586-025-03810-1
+ Nature, Published online: 2025-12-18; | doi:10.1038/d41586-025-03810-1
+ 2025-12-18
+ Nature
+ 10.1038/d41586-025-03810-1
+ https://www.nature.com/articles/d41586-025-03810-1
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10031-z
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-10031-zMazdutide versus dulaglutide in Chinese adults with type 2 diabetes]]>
+
+ Lixin GuoBo ZhangXia XueXin ZhangHanqing CaiHongwei JiangLili ZhangPing JinXiaojing WangZhifeng ChengSuhe ZhangJianlin GengYushan GuoHanbo HuQingyang MaLi LiHaiwei DuHan Han-ZhangFengtai XueHuan DengLei QianWenying Yang
+ doi:10.1038/s41586-025-10031-z
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-10031-z
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-10031-z
+ https://www.nature.com/articles/s41586-025-10031-z
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10026-w
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-10026-wMazdutide versus placebo in Chinese adults with type 2 diabetes]]>
+
+ Dalong ZhuJiajun ZhaoHanqing CaiXuan ChuShuangling XiuChengwei SongZhifeng ChengHongyi CaoHongwei JiangLili ZhangHaifang WangBimin ShiYanbing LiMing LiuBo FengFengtai XueHuan DengHaoyu LiLi LiYue LiQingyang MaLei Qian
+ doi:10.1038/s41586-025-10026-w
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-10026-w
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-10026-w
+ https://www.nature.com/articles/s41586-025-10026-w
+
+
+
+
+ https://www.nature.com/articles/s41586-025-10043-9
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-10043-9Author Correction: Neuroimmune cardiovascular interfaces control atherosclerosis]]>
+
+ Sarajo K. MohantaLi PengYuanfang LiShu LuTing SunLorenzo CarnevaleMarialuisa PerrottaZhe MaBenjamin FörsteraKaren StanicChuankai ZhangXi ZhangPiotr SzczepaniakMariaelvy BianchiniBorhan R. SaeedRaimondo CarnevaleDesheng HuRyszard NosalskiFabio PallanteMichael BeerDonato SantovitoAli ErtürkThomas C. MettenleiterBarbara G. KluppRemco T. A. MegensSabine SteffensJaroslav PelisekHans-Henning EcksteinRobert KleemannLivia HabenichtZiad MallatJean-Baptiste MichelJürgen BernhagenMartin DichgansGiuseppe D’AgostinoTomasz J. GuzikPeder S. OlofssonChangjun YinChristian WeberGiuseppe LemboDaniela CarnevaleAndreas J. R. Habenicht
+ doi:10.1038/s41586-025-10043-9
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-10043-9
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-10043-9
+ https://www.nature.com/articles/s41586-025-10043-9
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04080-7
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04080-7A unique archaeological site at Pompeii, Italy, reveals the secrets of peculiarly durable Roman building materials.]]>
+
+
+ doi:10.1038/d41586-025-04080-7
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04080-7
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04080-7
+ https://www.nature.com/articles/d41586-025-04080-7
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04079-0
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04079-0Tiny genetic variations between humans, Neanderthals and Denisovans might not be all they were cracked up to be.]]>
+
+
+ doi:10.1038/d41586-025-04079-0
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04079-0
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04079-0
+ https://www.nature.com/articles/d41586-025-04079-0
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03777-z
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03777-zKey mutations and animal spread could raise the risk to humans.]]>
+
+
+ doi:10.1038/d41586-025-03777-z
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03777-z
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03777-z
+ https://www.nature.com/articles/d41586-025-03777-z
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09873-4
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09873-4Using lipid nanoparticle delivery of mRNAs to the liver in aged mice, T cell function and declining immune cues can be restored.]]>
+
+ Mirco J. FriedrichJulie PhamJiakun TianHongyu ChenJiahao HuangNiklas KehlSophia LiuBlake LashFei ChenXiao WangRhiannon K. MacraeFeng Zhang
+ doi:10.1038/s41586-025-09873-4
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09873-4
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09873-4
+ https://www.nature.com/articles/s41586-025-09873-4
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09798-y
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09798-yDevelopment and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to meet them.]]>
+
+ Richard WolffNandita R. Garud
+ doi:10.1038/s41586-025-09798-y
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09798-y
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09798-y
+ https://www.nature.com/articles/s41586-025-09798-y
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09880-5
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09880-5Mu opioid receptor agonists with a preference for the non-GTP-bound state of the G protein promote GTP release, thereby potentiating antinociceptive effects of drugs such as morphine and fentanyl without also increasing their respiratory or cardiac effects.]]>
+
+ Edward L. StahlMatthew A. SwansonVuong Q. DangMichael D. CameronNicole M. KennedyThomas D. BannisterLaura M. Bohn
+ doi:10.1038/s41586-025-09880-5
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09880-5
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09880-5
+ https://www.nature.com/articles/s41586-025-09880-5
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09838-7
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09838-7An architecture inspired by Hopfield networks based on a programmable, stable, room-temperature optoelectronic oscillator-based photonics Ising machine is introduced that can be used to efficiently address optimization and combinatorics problems.]]>
+
+ Nayem Al-KayedCharles St-ArnaultHugh MorisonA. AadhiChaoran HuangAlexander N. TaitDavid V. PlantBhavin J. Shastri
+ doi:10.1038/s41586-025-09838-7
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09838-7
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09838-7
+ https://www.nature.com/articles/s41586-025-09838-7
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09890-3
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09890-3The 4D Nucleome Project demonstrates the use of genomic assays and computational methods to measure genome folding and then predict genomic structure from DNA sequence, facilitating the discovery of potential effects of genetic variants, including variants associated with disease, on genome structure and function.]]>
+
+ Job DekkerBetul Akgol OksuzYang ZhangYe WangMiriam K. MinskShuzhen KuangLiyan YangJohan H. GibcusNils KrietensteinOliver J. RandoJie XuDerek H. JanssensSteven HenikoffAlexander KukalevWillemin AndréaWarren Winick-NgRieke KempferAna PomboMiao YuPradeep KumarLiguo ZhangAndrew S. BelmontTakayo SasakiTom van SchaikLaura BruecknerDaan Peric-HupkesBas van SteenselPing WangHaoxi ChaiMinji KimYijun RuanRan ZhangSofia A. QuinodozPrashant BhatMitchell GuttmanWenxin ZhaoShu ChienYuan LiuSergey V. VenevDariusz PlewczynskiIbai Irastorza AzcarateDominik SzabóChristoph J. ThiemeTeresa SzczepińskaMateusz ChilińskiKaustav SenguptaMattia ConteAndrea EspositoAlex AbrahamRuochi ZhangYuchuan WangXingzhao WenQiuyang WuYang YangJie LiuLorenzo BoninsegnaAsli YildirimYuxiang ZhanAndrea Maria ChiarielloSimona BiancoLindsay LeeMing HuYun LiR. Jordan BarnettAshley L. CookDaniel J. EmersonClaire MarchalPeiyao ZhaoPeter J. ParkBurak H. AlverAndrew J. SchroederRahi NavelkarClara BakkerWilliam RonchettiShannon EhmsenAlexander D. VeitNils GehlenborgTing WangDaofeng LiXiaotao WangMario NicodemiBing RenSheng ZhongJennifer E. Phillips-CreminsDavid M. GilbertKatherine S. PollardFrank AlberJian MaWilliam S. NobleFeng Yue
+ doi:10.1038/s41586-025-09890-3
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09890-3
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09890-3
+ https://www.nature.com/articles/s41586-025-09890-3
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09843-w
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09843-wMetabolic and proteomic profiles derived from fossilized skeletal remains of animals enable inferences regarding physiological health and disease as well as diet to provide reconstructions of ancient soil, vegetation and palaeoclimate characteristics.]]>
+
+ Timothy G. BromageChristiane DenysChristopher Lawrence De JesusHediye Erdjument-BromageOttmar KullmerOliver SandrockFriedemann SchrenkMarc D. McKeeNatalie ReznikovGail M. AshleyBin HuSher B. PoudelAntoine SouronDaniel J. BussEran IttahJülide KubatSasan RabiehShoshana YakarThomas A. Neubert
+ doi:10.1038/s41586-025-09843-w
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09843-w
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09843-w
+ https://www.nature.com/articles/s41586-025-09843-w
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09770-w
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09770-wNeural circuits in adult mouse visual cortex are stabilized by astrocytes, which secrete CCN1, resulting in reduced plasticity and increased maturation of multiple cell types.]]>
+
+ Laura SanchoMatthew M. BoisvertTrinity EddyJillybeth BurgadoMinerva ContrerasLara Labarta-BajoEllen WangLisa TatsumiNicola J. Allen
+ doi:10.1038/s41586-025-09770-w
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09770-w
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09770-w
+ https://www.nature.com/articles/s41586-025-09770-w
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09827-w
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09827-wAn 11-qubit atom processor comprising two precision-placed nuclear spin registers of phosphorus in silicon is shown to achieve state-of-the-art Bell-state fidelities of up to 99.5%.]]>
+
+ Hermann EdlbauerJunliang WangA. M. Saffat-Ee HuqIan ThorvaldsonMichael T. JonesSaiful Haque MishaWilliam J. PappasChristian M. MoehleYu-Ling HsuehHenric BornemannSamuel K. GormanYousun ChungJoris G. KeizerLudwik KranzMichelle Y. Simmons
+ doi:10.1038/s41586-025-09827-w
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09827-w
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09827-w
+ https://www.nature.com/articles/s41586-025-09827-w
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09806-1
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09806-1Trends in global H2 sources and sinks are analysed from 1990 to 2020, and a comprehensive budget for the decade 2010–2020 is presented.]]>
+
+ Zutao OuyangRobert B. JacksonMarielle SaunoisJosep G. CanadellYuanhong ZhaoCatherine MorfopoulosPaul B. KrummelPrabir K. PatraGlen P. PetersFraser DennisonThomas GasserAlexander T. ArchibaldVivek AroraGabriel BaudoinNaveen ChandraPhilippe CiaisSteven J. DavisSarah FeronFangzhou GuoDidier HauglustaineChristopher D. JonesMatthew W. JonesEtsushi KatoDaniel KennedyJürgen KnauerSebastian LienertDanica LombardozziJoe R. MeltonJulia E.M.S. NabelMichael O’SullivanGabrielle PétronBenjamin PoulterJoeri RogeljDavid Sandoval CallePete SmithParvadha SuntharalingamHanqin TianChenghao WangAndy Wiltshire
+ doi:10.1038/s41586-025-09806-1
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09806-1
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09806-1
+ https://www.nature.com/articles/s41586-025-09806-1
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09858-3
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09858-3Scanning tunnelling microscopy is used to image pristine electrostatically defined quantum Hall edge states in graphene with high spatial resolution and demonstrate their interaction-driven restructuring.]]>
+
+ Jiachen YuHaotan HanKristina G. WolinskiRuihua FanAmir S. MohammadiTianle WangTaige WangLiam CohenKenji WatanabeTakashi TaniguchiAndrea F. YoungMichael P. ZaletelAli Yazdani
+ doi:10.1038/s41586-025-09858-3
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09858-3
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09858-3
+ https://www.nature.com/articles/s41586-025-09858-3
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09841-y
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09841-yThe prevalence of Alzheimer’s disease neuropathological changes is reported based on blood-based biomarkers in a Norwegian population-based cohort.]]>
+
+ Dag AarslandAnita Lenora SundeDiego A. Tovar-RiosAntoine LeuzyTormod FladbyHenrik ZetterbergKaj BlennowKübra TanGiovanni De SantisYara YakoubBurak ArslanHanna HuberIlaria PolaLana GrötschelGuglielmo Di MolfettaHåvard K. SkjellegrindGeir SelbaekNicholas J. Ashton
+ doi:10.1038/s41586-025-09841-y
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09841-y
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09841-y
+ https://www.nature.com/articles/s41586-025-09841-y
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09818-x
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09818-xReanalysis of radiometric data from Cassini indicates that Titan does not contain a subsurface ocean, as strong tidal dissipation observed in its gravity field is not consistent with the presence of a liquid layer.]]>
+
+ Flavio PetriccaSteven D. VanceMarzia ParisiDustin BuccinoGael CascioliJulie Castillo-RogezBrynna G. DowneyFrancis NimmoGabriel TobieBaptiste JournauxAndrea MagnaniniUla JonesMark PanningAmirhossein BagheriAntonio GenovaJonathan I. Lunine
+ doi:10.1038/s41586-025-09818-x
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09818-x
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09818-x
+ https://www.nature.com/articles/s41586-025-09818-x
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09884-1
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09884-1Hepatocyte organoids derived directly from human tissue enable long-term hepatocyte expansion and can be combined with portal mesenchyme and cholangiocyte organoids to form a donor-specific periportal liver assembloid system.]]>
+
+ Lei YuanSagarika DawkaYohan KimAnke LiebertFabian RostRobert Arnes-BenitoFranziska BaenkeChristina GötzDavid Long Hin TsangAndrea SchuhmannAnna ShevchenkoRoberta Rezende de CastroSeunghee KimAleksandra SljukicAnna M. DowbajAndrej ShevchenkoDaniel SeehoferDongho ChoiGeorg DammDaniel E. StangeMeritxell Huch
+ doi:10.1038/s41586-025-09884-1
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09884-1
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09884-1
+ https://www.nature.com/articles/s41586-025-09884-1
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09875-2
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09875-2A detailed spatiotemporal roadmap of the human female and male reproductive tracts during key periods of sexual differentiation provides new cellular and molecular insights into how early axial gradients lead to specific cell lineages and tissue structures.]]>
+
+ Valentina LorenziCecilia Icoresi-MazzeoCharlotte CassieNadav YayonElias R. Ruiz-MoralesCarmen Sancho-SerraRyan ColliganFrederick C. K. WongMagda MarečkováElizabeth TuckKenny RobertsTong LiMarc-Antoine JacquesJames AshcroftXiaoling HeBerta CrespoBatuhan CakirSimon MurrayYong GuAlexander V. PredeusMartin PreteIva KelavaRoger BarkerLuz Garcia-AlonsoJohn C. MarioniRoser Vento-Tormo
+ doi:10.1038/s41586-025-09875-2
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09875-2
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09875-2
+ https://www.nature.com/articles/s41586-025-09875-2
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09887-y
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09887-yAfter spinal cord injury, lesion-remote astrocytes acquire heterogeneous, spatially restricted reactivity states that shape neuroinflammation, neural repair and neurological recovery.]]>
+
+ Sarah McCallumKeshav B. SureshTimothy S. IslamManish K. TripathiAnn W. SaustadOksana ShelestAditya PatilDavid LeeBrandon KwonKatherine LeitholfInga YenokianSophia E. ShakaConnor H. BeveridgePalak ManchandraCaitlin E. RandolphGordon P. MearesRanjan DuttaJasmine PlummerVinicius F. CalsavaraRiki KawaguchiSimon R. V. KnottGaurav ChopraJoshua E. Burda
+ doi:10.1038/s41586-025-09887-y
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09887-y
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09887-y
+ https://www.nature.com/articles/s41586-025-09887-y
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09814-1
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09814-1Gas-phase actinium monofluoride (AcF) has been produced and spectroscopically studied at the CERN-ISOLDE radioactive ion beam facility; the results highlight the potential of 227AcF for exceptionally sensitive searches of CP violation.]]>
+
+ M. Athanasakis-KaklamanakisM. AuA. KyuberisC. ZülchK. GaulH. WibowoL. SkripnikovL. LalanneJ. R. ReillyÁ. KoszorúsS. BaraJ. BallofR. BergerC. BernerdA. BorschevskyA. A. BreierK. ChrysalidisT. E. CocoliosR. P. de GrooteA. DorneJ. DobaczewskiC. M. Fajardo ZambranoK. T. FlanaganS. FranchooJ. D. JohnsonR. F. Garcia RuizD. HanstorpS. KujanpääY. C. LiuK. M. LynchA. McGloneN. S. MosyaginG. NeyensM. NicholsL. NiesF. PastranaS. RotheW. RyssensB. van den BorneJ. WessolekS. G. WilkinsX. F. Yang
+ doi:10.1038/s41586-025-09814-1
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09814-1
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09814-1
+ https://www.nature.com/articles/s41586-025-09814-1
+
+
+
+
+ https://www.nature.com/articles/s41586-025-09842-x
+
+ Nature, Published online: 17 December 2025; doi:10.1038/s41586-025-09842-xA three-dimensional (3D) nanofabrication platform based on metalens-generated focal spot arrays is introduced to parallelize two-photon lithography beyond centimetre-scale write field areas, revealing the potential of 3D nanolithography towards wafer-scale production.]]>
+
+ Songyun GuChenkai MaoAnna Guell IzardSarvesh SadanaDongping Terrel-PerezMagi Mettry-YassaWonjin ChoiWenjie ZhouHujie YanZiran ZhouTravis MasseyAlex AbelsonYou ZhouSijia HuangChiara DaraioThejaswi Umanath TumkurJonathan A. FanXiaoxing Xia
+ doi:10.1038/s41586-025-09842-x
+ Nature, Published online: 2025-12-17; | doi:10.1038/s41586-025-09842-x
+ 2025-12-17
+ Nature
+ 10.1038/s41586-025-09842-x
+ https://www.nature.com/articles/s41586-025-09842-x
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03820-z
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03820-zVideo-call glitches might seem harmless, but they can reduce people’s chances of getting hired, closing a business deal or following a doctor’s recommendation. Human brains expect video calls to feel like in-person conversations. When glitches break that illusion, it feels unsettling and strange, harming judgements of trustworthiness, likeability and credibility.]]>
+
+
+ doi:10.1038/d41586-025-03820-z
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03820-z
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03820-z
+ https://www.nature.com/articles/d41586-025-03820-z
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03613-4
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03613-4Avian influenza is devastating poultry operations, spreading in dairy cattle and infecting farm workers. Why isn’t the United States doing more to stop it?]]>
+
+ Cassandra Willyard
+ doi:10.1038/d41586-025-03613-4
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03613-4
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03613-4
+ https://www.nature.com/articles/d41586-025-03613-4
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04024-1
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04024-1The colour of regret.]]>
+
+ Nathalie Béchon
+ doi:10.1038/d41586-025-04024-1
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04024-1
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04024-1
+ https://www.nature.com/articles/d41586-025-04024-1
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03505-7
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03505-7Immense progress in gene editing, drug discovery and conservation are just some of the reasons to be cheerful about 2025.]]>
+
+ Katie Kavanagh
+ doi:10.1038/d41586-025-03505-7
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03505-7
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03505-7
+ https://www.nature.com/articles/d41586-025-03505-7
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03489-4
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03489-4A chemist faces a classic early-career dilemma: what should they do next, and how do they start?]]>
+
+ Miles Lizak
+ doi:10.1038/d41586-025-03489-4
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03489-4
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03489-4
+ https://www.nature.com/articles/d41586-025-03489-4
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04015-2
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04015-2Experiments have revealed that the interaction between a hydrogen-rich atmosphere and a molten planet leads to high levels of water production. Through this process, planets could be enriched with water during their formation, altering their chemistry, evolution and, possibly, habitability.]]>
+
+
+ doi:10.1038/d41586-025-04015-2
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04015-2
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04015-2
+ https://www.nature.com/articles/d41586-025-04015-2
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03607-2
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03607-2The death toll and economic damage associated with flu highlight its role as one of the most harmful viruses in history.]]>
+
+ Bianca Nogrady
+ doi:10.1038/d41586-025-03607-2
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03607-2
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03607-2
+ https://www.nature.com/articles/d41586-025-03607-2
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04135-9
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04135-9Plasma physicist Nuno Loureiro was helping to develop clean-energy fusion devices.]]>
+
+ Rachel FieldhouseMohana BasuElizabeth Gibney
+ doi:10.1038/d41586-025-04135-9
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04135-9
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04135-9
+ https://www.nature.com/articles/d41586-025-04135-9
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03598-0
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03598-0Influenza isn’t just a respiratory disease. Measures to stop its transmission, such as vaccination, could prevent thousands of heart-attack deaths.]]>
+
+ Ashish Jha
+ doi:10.1038/d41586-025-03598-0
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03598-0
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03598-0
+ https://www.nature.com/articles/d41586-025-03598-0
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03602-7
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03602-7Avian influenza is sweeping the globe and infecting dozens of species. Advocates of an approach called One Health are calling for broad surveillance of wildlife, livestock and pets.]]>
+
+ Sarah DeWeerdt
+ doi:10.1038/d41586-025-03602-7
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03602-7
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03602-7
+ https://www.nature.com/articles/d41586-025-03602-7
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04133-x
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04133-xA survey of Alzheimer’s disease prevalence in Norway confirms earlier estimates and might show how education level relates to risk.]]>
+
+ Asher Mullard
+ doi:10.1038/d41586-025-04133-x
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04133-x
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04133-x
+ https://www.nature.com/articles/d41586-025-04133-x
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04119-9
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04119-9Try these 12 questions to test your knowledge of News & Views and Research Briefing articles published in 2025.]]>
+
+ Mary Abraham
+ doi:10.1038/d41586-025-04119-9
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04119-9
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04119-9
+ https://www.nature.com/articles/d41586-025-04119-9
+
+
+
+ Nature Podcast festive spectacular 2025]]>
+ https://www.nature.com/articles/d41586-025-04140-y
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04140-yMemorable science-themed gifts, games, seasonal songs, and Nature’s 10.]]>
+ Nature Podcast festive spectacular 2025]]>
+ Benjamin ThompsonNick Petrić Howe
+ doi:10.1038/d41586-025-04140-y
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04140-y
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04140-y
+ https://www.nature.com/articles/d41586-025-04140-y
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03612-5
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03612-5Although development of a jab for the H5N1 strain of avian flu is well under way, other strains are receiving less attention — and political obstacles to research could hamper progress.]]>
+
+ Charles Schmidt
+ doi:10.1038/d41586-025-03612-5
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03612-5
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03612-5
+ https://www.nature.com/articles/d41586-025-03612-5
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04044-x
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04044-xA high-performance silicon-based quantum processor has been developed in which the spins of nine phosphorus nuclei — divided into two groups, or registers — and two shared electrons act as quantum bits (qubits). The modular design of this 11-qubit processor opens the door to a scalable approach to building large, reliable quantum-computing processors.]]>
+
+
+ doi:10.1038/d41586-025-04044-x
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04044-x
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04044-x
+ https://www.nature.com/articles/d41586-025-04044-x
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03608-1
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03608-1Scientists are deploying an array of technologies that are making a vaccine against all varieties of influenza seem more achievable.]]>
+
+ Neil Savage
+ doi:10.1038/d41586-025-03608-1
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03608-1
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03608-1
+ https://www.nature.com/articles/d41586-025-03608-1
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03808-9
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03808-9Our genomes are highly structured, which facilitates gene regulation. An ambitious project has catalogued the organization of DNA in the nuclei of human cells.]]>
+
+ Elzo de Wit
+ doi:10.1038/d41586-025-03808-9
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03808-9
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03808-9
+ https://www.nature.com/articles/d41586-025-03808-9
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04082-5
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04082-5Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.]]>
+
+ Heidi Ledford
+ doi:10.1038/d41586-025-04082-5
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04082-5
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04082-5
+ https://www.nature.com/articles/d41586-025-04082-5
+
+
+
+
+ https://www.nature.com/articles/d41586-025-04134-w
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-04134-wMuch of the National Center for Atmospheric Research’s non-climate portfolio will be dispersed, the White House says.]]>
+
+ Alexandra Witze
+ doi:10.1038/d41586-025-04134-w
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-04134-w
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-04134-w
+ https://www.nature.com/articles/d41586-025-04134-w
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03599-z
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03599-zFlu-jab efficacy is often unimpressive. Improvements could come through nasal delivery.]]>
+
+ Troy Sutton
+ doi:10.1038/d41586-025-03599-z
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03599-z
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03599-z
+ https://www.nature.com/articles/d41586-025-03599-z
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03606-3
+
+ Nature, Published online: 17 December 2025; doi:10.1038/d41586-025-03606-3Researchers are striving to understand the impact a phenomenon known as original antigenic sin has on immunity to the virus.]]>
+
+ Amanda B. Keener
+ doi:10.1038/d41586-025-03606-3
+ Nature, Published online: 2025-12-17; | doi:10.1038/d41586-025-03606-3
+ 2025-12-17
+ Nature
+ 10.1038/d41586-025-03606-3
+ https://www.nature.com/articles/d41586-025-03606-3
+
+
+
+
+ https://www.nature.com/articles/d41586-025-03740-y
+
+ Nature, Published online: 16 December 2025; doi:10.1038/d41586-025-03740-yScientists discuss concerns that genetic manipulation could lead to disease outbreaks, and Nature is gifted an unusual scientific instrument, in our weekly dip into the archive.]]>
+
+
+ doi:10.1038/d41586-025-03740-y
+ Nature, Published online: 2025-12-16; | doi:10.1038/d41586-025-03740-y
+ 2025-12-16
+ Nature
+ 10.1038/d41586-025-03740-y
+ https://www.nature.com/articles/d41586-025-03740-y
+
+
+
+ Great British Sewing Bee success]]>
+ https://www.nature.com/articles/d41586-025-03536-0
+
+ Nature, Published online: 16 December 2025; doi:10.1038/d41586-025-03536-0A research background and a passion for sewing inspired by her father helped Yasmin Proctor-Kent to reach the finals of the 2025 television competition.]]>
+ Great British Sewing Bee success]]>
+ Yasmin Proctor-Kent
+ doi:10.1038/d41586-025-03536-0
+ Nature, Published online: 2025-12-16; | doi:10.1038/d41586-025-03536-0
+ 2025-12-16
+ Nature
+ 10.1038/d41586-025-03536-0
+ https://www.nature.com/articles/d41586-025-03536-0
+
+
+