This also a great defense to hide some of your weaker players as they get required plays.
The 53 defense has 5 down linemen, 3 linebackers.  The secondary consist of 2 cornerbacks and a safety.  The great thing about this defense is that you only have to find 3 linebackers. Where as the 44 you need 4 linebackers.  It also has 5 down linemen which will allow your 3 linebackers to be free off blocks and make plays. This also a great defense to hide some of your weaker players as they get required plays.