Relative and absolute configuration, sequence rules, D & L and R & S systems of nomenclature.
Stereochemistry: Concept of isomerism, Types of isomerism; Optical isomerism – elements of symmetry, molecular chirality, enantiomers, stereogenic centre, optical activity, properties of enantiomers, chiral and achiral molecules with two stereogenic centres, diasteromers, threo and erythro diastereomers, meso compounds, resolution of enantiomer, inversion, retention and racemisation. Relative and absolute configuration, sequence rules, D & L and R & S systems of nomenclature. Geometric isomerism – determination of configuration of geometric isomers, E & Z system of nomenclature, geometric isomerism in oximes and alicyclic compounds. Conformational isomerism – conformational analysis of ethane and n-butane; conformations of cyclohexane, axial and equatorial bonds, conformation of monosubstituted cyclohexane derivatives, Newman projection and Sawhorse formulae, Fischer and flying wedge formulae, difference between configuration and conformation. (10)