Data & Ethics
Ancestry-Aware Modeling
This software implements ancestry-aware antibody design, considering genetic and immunological variations across different populations. The model:
- Incorporates HLA type matching (currently supporting 2 matches)
- Considers ancestry-specific immune responses
- Adapts to metabolic variations
Ethics and Oversight
- All sequences are logged with ancestry context
- Ethical validation performed via CoreConscience system
- Full traceability of design decisions
- Rejection memory maintains record of discarded designs
Ethics Statement
This software is designed to promote inclusive and ethical antibody development. We are committed to preventing misuse and ensuring equitable benefit across populations.
Concerns or Questions
For ethics-related inquiries, please contact: Jonathan Harrison Light ([email protected]) ORCID: 0009-0003-7005-8187
Cross-References
- GitHub Release: v1.0.0
- Hugging Face Model: healdette/protgpt2-ancestry
- DOI: 10.57967/hf/5917