N. Scott Adzick, MD, MMM, FACS, FAAP
N. Scott Adzick, MD, MMM, FACS, FAAP, is Surgeon-in-Chief of Children's Hospital of Philadelphia and the founder and Director of the Center for Fetal Diagnosis and Treatment.
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2020

Rintoul NE, Keller RL, Walsh WF, Burrows PK, Thom EA, Kallan MJ, Howell LJ, Adzick NS, MOMS Investigators. The Management of Myelomeningocele Study: Short-Term Neonatal Outcomes. Fetal Diagn Ther. 2020 Aug 31;1-8. doi: 10.1159/000509245. PMID: 32866951

Two's Company: Multiple Thoracic Lesions on Prenatal US and MRI. Oliver ER, DeBari SE, Didier RA, Johnson AM, Khalek N, Peranteau WH, Howell LJ, Adzick NS, Coleman BG. Fetal Diagn Ther. 2020 Jun 29;1-11. doi: 10.1159/000507783. Online ahead of print. Read the abstract.

Surgical treatment of congenital hyperinsulinism. Adzick NS. Semin Pediatr Surg. 2020 Jun;29(3):150924. doi: 10.1016/j.sempedsurg.2020.150924. Epub 2020 May 17. Read more here.

Oliver ER, Heuer GG, Thom EA, Burrows PK, Didier RA, DeBari SE, Martin-Saavedra JS, Moldenhauer JS, Jatres J, Howell LJ, Adzick NS, Coleman BG. Myelomeningocele Sac Associated With Worse Lower-Extremity Neurological Sequelae: Evidence for Prenatal Neural Stretch Injury? Ultrasound Obstet Gynecol. 2020 Jun;55(6):740-746. doi: 10.1002/uog.21891. Read the abstract.

Houtrow AJ, Thom EA, Fletcher JM, Burrows PK, Adzick NS, Thomas NH, Brock III JW, Cooper T, Lee H, Bilaniuk L, Glenn OA, Pruthi S, MacPherson C, Farmer DL, Johnson MP, Howell LJ, Gupta N, Walker WO. “Prenatal Repair of Myelomeningocele and School-Age Functional Outcomes,” Pediatrics, online January 24, 2020.

2019

Brock JW 3rd, Thomas JC, Baskin LS, Zderic SA, Thom EA, Burrows PK, Lee H, Houtrow AJ, Macpherson C, Adzick NS. Effect of Prenatal Repair of Myelomeningocele on Urological Outcomes at School Age. J Urol. 2019 May 10; [Epub ahead of print] PMID: 31075056

Baumgarten HD, Bauer AJ, Isaza A, Mostoufi-Moab S, Kazahaya K, Adzick NS. Surgical management of pediatric thyroid disease: Complication rates after thyroidectomy at the Children's Hospital of Philadelphia high-volume Pediatric Thyroid Center. J Pediatr Surg. 2019 Feb 28. pii: S0022-3468(19)30122-8. doi: 10.1016/j.jpedsurg.2019.02.009. [Epub ahead of print]

Pogoriler J, Swarr D, Krieger P, Adzick NS, Peranteau WH: Congenital cystic lung lesions: Redefining the natural distribution of subtypes and risk of malignancy. Am J Surg Pathology 43:47-55, 2019.

Jaimes C, Delgado J, Cunnane MB, Hedrick HL, Adzick NS, Gee MS, Victoria T: Does 3T fetal MRI induce adverse acoustic effects in the neonate? A preliminary study comparing postnatal auditory test performance of fetuses scanned at 1.5 and 3T. Pediatric Radiology 49:37-45, 2019.

Rivas A, Epelman M, Danzer E, Adzick NS, Victoria T. Prenatal MR imaging features of Caroli syndrome in association with autosomal recessive polycystic kidney disease. Radiol Case Rep. 2019 Feb;14(2):265-268. PMID: 30510609

Oliver ER, DeBari SE, Adams SE, Didier RA, Horii SC, Victoria T, Hedrick HL, Adzick NS, Howell LJ, Moldenhauer JS, Coleman BG. Congenital diaphragmatic hernia sacs: prenatal imaging and associated postnatal outcomes. Pediatr Radiol. 2019 Jan 11. doi: 10.1007/s00247-018-04334-9. [Epub ahead of print]

Adzick NS, De Leon DD, States LJ, Lord K, Bhatti TR, Becker SA, Stanley CA. Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children. J Pediatr Surg. 2019 Jan;54(1):27-32. doi: 10.1016/j.jpedsurg.2018.10.030. Epub 2018 Oct 5.

2018

Danzer E, Hoffman C, D'Agostino J, Ryan M, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Rate and risk factors associated with autism spectrum disorder in congenital diaphragmatic hernia. Journal of Autism and Developmental Disorders48:2112-2121, 2018.

Farmer DL, Thom EA, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Gupta N, Adzick NS for the MOMS Investigators: The Management of the Myelomeningocele Study: Full cohort 30 month pediatric outcomes. Am J Obstet Gyn218:256.e1-13, 2018.

MacFarland S, Bauer AJ, Adzick NS, Surrey LF, Noyes J, Kazahaya K, Baloch Z, Mostoufi-Moab S: Disease burden and outcome in pediatric and young adults with concurrent Graves Disease and differentiated thyroid carcinoma. Journal of Clinical Endocrinology and Metabolism 103:2918-2925, 2018.

Mostoufi-Moab S. Sullivan L, LiVolsi V, Li Y, Beaudenon-Huibregtse S, Kazahaya K, Adzick NS, Baloch Z, Labourier E, Bauer AJ: Molecular testing for oncogenic gene alterations in pediatric thyroid lesions. Thyroid 28:60-67, 2018.

Samuels SL, Surrey LF, Hawkes CP, Amberge M, Mostoufi-Moab S, Langer JE, Adzick NS, Kazahaya K, Bhatti T, Baloch Z, LiVolsi BA, Bauer AJ: Characteristics of follicular variant papillary thyroid carcinoma in a pediatric cohort. Journal of Clinical Endocrinology and Metabolism 103:1639-1648, 2018.

Fraga MV, Laje P, Peranteau WH, Hedrick HL, Khalek N, Gebb JS, Moldenhauer JS, Johnson MP, Flake AW, Adzick NS: The influence of gestational age, delivery mode, and abdominal wall closure method in neonates with uncomplicated gastroschisis. Pediatr Surg Int 34:415-9, 2018.

Riley JS, Urwin JW, Oliver ER, Coleman BG, Khalek N, Moldenhauer JS, Gebb J, Hedrick HL, Spinner SS, Adzick NS, Peranteau WH: Prenatal growth characteristics and pre/postnatal management of bronchopulmonary sequestrations. J Pediatr Surg 53:265-269, 2018.

Victoria T, Johnson AM, Adzick NS, Hedrick HL, Shellock FG: Evaluation of MRI artifacts and safety issues associated with the occlusion balloon used for Fetoscopic Endoluminal Tracheal Occlusion (FETO). Fetal Diagnosis and Therapy 44:179-183, 2018.

Danzer E, Hoffman C, D'Agostino J, Connelly JT, Waqar LN, Gerdes M, Bernbaum J, Rintoul NE, Herkert LM, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Short-term neurodevelopmental outcome in congenital diaphragmatic hernia: The impact of extracorporeal membrane oxygenation and timing of repair. Pediatric Critical Care Medicine 19:64-74, 2018.

Danzer E, Hoffman C, D’Agostino JA, Boelig MM, Gerdes M, Bernbaum J, Rosenthal H, Waqar LN, Rintoul NE, Herkert LM, Kallan MJ, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Short-term neurodevelopmental outcome in children born with high-risk congenital lung lesions. Annals of Thoracic Surgery 105:1827-1834, 2018.

Swarr DT, Peranteau WH, Pogoriler J, Frank DB, Adzick NS, Hedrick HL, Morley M, Zhou S, Morrisey EE: Novel molecular and phenotypic insights into congenital pulmonary airway malformations. American Journal of Respiratory and Critical Care Medicine 197:1328-1339, 2018.

Russell KW, Nance ML, Adzick NS, Laje P. Meconium aspiration syndrome requiring ECMO in newborns with gastroschisis: incidence and surgical outcomes. Pediatr Surg Int. 2018 Nov 16; PMID: 30443738

Didier RA, DeBari SE, Oliver ER, Gebb JS, Howell LJ, Hedrick HL, Adzick NS, Coleman BG. Secondary Imaging Findings Aid in Prenatal Diagnosis and Characterization of Congenital Diaphragmatic Hernia: Role of an Abnormal Orientation of Vascular Structures and Gallbladder Position. J Ultrasound Med. 2018 Sep 23;. [Epub ahead of print] PMID: 30244484

Farmer DL, Adzick NS. Reply to Manuscript # L18-092AR1 " A clinician's concerns about motor functions Outcomes of fetal Surgery for Myelomeningocele." Am J Obstet Gynecol. 2018 Sep 21; [Epub ahead of print] PMID: 30248309

Oliver ER, DeBari SE, Horii SC, Pogoriler JE, Victoria T, Khalek N, Howell LJ, Adzick NS, Coleman BG. Congenital Lobar Overinflation: A Rare Enigmatic Lung Lesion on Prenatal Ultrasound and Magnetic Resonance Imaging. J Ultrasound Med. 2018 Sep 12. doi: 10.1002/jum.14801. [Epub ahead of print]

Fraga MV, Giaccone A, Adzick NS. Respiratory morbidities in late preterm and term infants with myelomeningocele. J Perinatol. 2018 Aug 30;. [Epub ahead of print] PMID: 30166620 [PubMed - as supplied by publisher]

Victoria T, Srinivasan AS, Pogoriler J, Kreiger PA, Laje P, Oliver ER, Danzer E, Johnson AM, Moldenhauer JS, Peranteau WH, Adzick NS. The rare solid fetal lung lesion with T2-hypointense components: prenatal imaging findings with postnatal pathological correlation. Pediatr Radiol. 2018 Jul 14; PMID: 30008034

Gibson CE, Boodhansingh KE, Li C, Conlin L, Chen P, Becker SA, Bhatti T, Bamba V, Adzick NS, De Leon DD, Ganguly A, Stanley CA. Congenital Hyperinsulinism in Infants with Turner Syndrome: Possible Association with Monosomy X and KDM6A Haploinsufficiency. Horm Res Paediatr. 2018 Jun 14; 1-10. [Epub ahead of print] PMID: 29902804

Riley JS, Antiel RM, Rintoul NE, Ades AM, Waqar LN, Lin N, Herkert LM, D'Agostino JA, Hoffman C, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Reduced oxygen concentration for the resuscitation of infants with congenital diaphragmatic hernia. J Perinatol. 2018 Jun 11. [Epub ahead of print]

Baumgarten HD, Gebb JS, Khalek N, Moldenhauer JS, Johnson MP, Peranteau WH, Hedrick HL, Adzick NS, Flake AW. Preemptive Delivery and Immediate Resection for Fetuses with High-Risk Sacrococcygeal Teratomas. Fetal Diagn Ther. 2018 May 7;:1-8. [Epub ahead of print] PMID: 29734172

Victoria T, Andronikou S, Bowen D, Laje P, Weiss DA, Johnson AM, Peranteau WH, Canning DA, Adzick NS. Fetal anterior abdominal wall defects: prenatal imaging by magnetic resonance imaging. Pediatr Radiol. 2018 Apr;48(4):499-512. PMID: 29550866

Wong KKY, Flake AW, Tibboel D, Rottier RJ, Tam PKH. Congenital pulmonary airway malformation: advances and controversies. Lancet Child Adolesc Health. 2018 Apr;2(4):290-297. PMID: 30169300

Laje P, Fraga MV, Peranteau WH, Hedrick HL, Khalek N, Gebb JS, Moldenhauer JS, Johnson MP, Flake AW, Adzick NS. Complex gastroschisis: Clinical spectrum and neonatal outcomes at a referral center. J Pediatr Surg. 2018 Mar 14;. [Epub ahead of print] PMID: 29628208

Victoria T, Zhu X, Lachman R, Dwek JR, Johnson AM, Epelman M, Oliver ER, Adzick NS, Biko DM: What is new in skeletal dysplasias? AJR Am J Roentgenol. 2018 May;210(5):1022-1033. doi: 10.2214/AJR.17.19337. Epub 2018 Mar 12.

Gebb JS, Khalek N, Qamar H, Ozcan T, Johnson MP, Oliver ER, Coleman BG, Peranteau WH, Hedrick HL, Flake AW, Adzick NS, Moldenhauer JS: High tumor volume to fetal weight ratio is associated with worse fetal outcomes and increased maternal risks in fetuses with sacrococcygeal teratoma. Fetal Diagn Ther. 2019;45(2):94-101. doi: 10.1159/000486782. Epub 2018 Mar 1.

Farmer DL, Thom EA, Brock JW, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Gupta N5, Adzick NS. Management of Myelomeningocele Study Investigators. The Management of Myelomeningocele Study: full cohort 30-month pediatric outcomes. Am J Obstet Gynecol. 2018 Feb;218(2): Epub 2017 Dec 12. PMID: 29246577

Swarr DT, Peranteau WH, Pogoriler J, Frank DB, Adzick NS, Hedrick HL, Morley M, Zhou S, Morrisey EE. Novel Molecular and Phenotypic Insights into Congenital Lung Malformations. Am J Respir Crit Care Med. 2018 Jan 12. doi: 10.1164/rccm.201706-1243OC. [Epub ahead of print] PubMed PMID: 29328793.

Victoria T, Danzer E, Oliver ER, Edgar JC, Iyoob S, Partridge EA, Johnson AM, Peranteau WH, Coleman BG, Flake AW, Johnson MP, Hedrick HL, Adzick NS: Right congenital diaphragmatic hernias: Is there a correlation between prenatal lung volume and postnatal survival, as in isolated left diaphragmatic hernias? Fetal Diagnosis and Therapy 2018; 43: 12-18, January 2018.

2017

Yu PT, Fenton SJ, Delaplain P, Vrecenak J, Adzick NS, Nance ML, Guner Y: The management of choledocholithiasis in the infant: Case series and literature review. J Pediatr Surg Case Reports 29:52-58, 2017.

Oliver ER, Coleman BG, DeBari SE, Victoria T, Looney DM, Horii SC, Moldenhauer JS, Langer JE, Howell LJ, Pawel BR, Adzick NS. Fetal Lymphatic Malformations: More Variable Than We Think? J Ultrasound Med. 2017 Jan 27. Doi:10.7863/ultra.16.04071. [Epub ahead of print]

Peranteau WH, Iyoob SD, Boelig MM, Khalek N, Moldenhauer JS, Johnson MP, Hedrick HL, Flake AW, Coleman BG, Adzick NS. Prenatal growth characteristics of lymphatic malformations. J Pediatr Surg. 2017 Jan;52(1):65-68.

Oliver ER, DeBari SE, Giannone MM, Pogoriler JE, Johnson AM, Horii SC, Gebb JS, Howell LJ, Adzick NS, Coleman BG: Going with the Flow: An Aid in Differentiating Bronchopulmonary Sequestrations and Hybrid Lesions. J Ultrasound Med. 2017 Aug 10. doi: 10.1002/jum.14346. [Epub ahead of print].

Heuer GG, Moldenhauer JS, Adzick NS. Prenatal surgery for myelomeningocele: review of the literature and future directions. Childs Nerv Syst. 2017 Jul;33(7):1149-1155. Doi: 10.1007/s00381-017-3440-z. Epub 2017 May 17.

Kim AG, Danzer E, Moldenhauer JS, Khalek N, McClain LE, Waqar LN, Hedrick HL, Johnson MP, Adzick NS, Peranteau WH, Flake AW. Amniotic Fluid Concentrations of Glial Fibrillary Acidic Protein Do Not Correlate with Prenatal Metrics in Fetuses with Myelomeningocele. Fetal Diagn Ther. 2017 Jul 29. Doi: 10.1159/000478258. [Epub ahead of print].

Moldenhauer JS, Adzick NS. Fetal surgery for myelomeningocele: After the Management of Myelomeningocele Study (MOMS). Semin Fetal Neonatal Med. 2017 Oct 11. pii: S1744-165X(17)30093-8. doi: 10.1016/j.siny.2017.08.004. [Epub ahead of print]

2016

Unolt M, DiCairano L, Schlechtweg K, Barry J, Howell L, Kasperski S, Nance M, Adzick NS, Zackai EH, McDonald-McGinn DM. Congenital diaphragmatic hernia in 22q11.2 deletion syndrome. Am J Med Genet A. 2016 Sep 28. doi: 10.1002/ajmg.a.37980.

Danzer E, Hoffman C, D'Agostino JA, Gerdes M, Bernbaum J, Antiel RM, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcomes at 5 years of age in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Aug 30. pii: S0022-3468(16)30284-6. doi: 10.1016/j.jpedsurg.2016.08.008.

Antiel RM, Adzick NS, Thom EA, Burrows PK, Farmer DL, Brock JW 3rd, Howell LJ, Farrell JA, Houtrow AJ; Management of Myelomeningocele Study Investigators. Impact on family and parental stress of prenatal vs postnatal repair of myelomeningocele. Am J Obstet Gynecol. 2016 Jun 2. pii: S0002-9378(16)30264-2. doi: 10.1016/j.ajog.2016.05.045.

Johnson MP, Bennett KA, Rand L, Burrows PK, Thom EA, Thom LJ, Farrell JA, Dabrowiak ME, Brock JW 3rd, Farmer DL, Adzick NS, Management of Myelomeningocele Study Investigators. The Management of Myelomeningocele Study: obstetrical outcomes and risk factors for obstetrical complications following prenatal surgery. Am J Obstet Gynecol. 2016 Aug 2. pii: S0002-9378(16)30526-9. doi: 10.1016/j.ajog.2016.07.052.

Rychik J, Khalek N, Gaynor JW, Johnson MP, Adzick NS, Flake AW, Hedrick HL. Fetal Intrapericardial Teratoma: Natural History and Management Including Successful In Utero Surgery. Am J Obstet Gynecol. 2016 Aug 13. pii: S0002-9378(16)30575-0. doi: 10.1016/j.ajog.2016.08.010.

Lin EE, Moldenhauer JS, Tran KM, Cohen DE, Adzick NS. Anesthetic Management of 65 Cases of Ex Utero Intrapartum Therapy: A 13-Year Single-Center Experience. Anesth Analg. 2016 Aug;123(2):411-7. doi: 10.1213/ANE.0000000000001385.

Soni S, Moldenhauer JS, Spinner SS, Rendon N, Khalek N, Martinez-Poyer J, Johnson MP, Adzick NS: Chorioamniotic membrane separation and preterm premature rupture of membranes complicating in utero myelomeningocele repair. Am J Obstet Gynecol. 2016 May;214(5):647.e1-7. doi: 10.1016/j.ajog.2015.12.003. Epub 2015 Dec 12.

Peranteau WH, Adzick NS: Prenatal surgery for myelomeningocele. Curr Opin Obstet Gynecol. 2016 Apr;28(2):111-8. doi: 10.1097/GCO.0000000000000253.

Coughlin CC, Roy SM, Arkin LM, MD, Adzick NS, Yan AC, De León DD, Rubin AI: Iatrogenic necrolytic migratory erythema in an infant receiving glucagon therapy for congenital hyperinsulinism. Pediatr Dermatol. 2016 Mar;33(2):e43-e47. doi: 10.1111/pde.12741. Epub 2015 Dec 9.

Laje P, Hedrick HL, Flake AW, Adzick NS, Peranteau WH: Delayed abdominal closure after congenital diaphragmatic hernia repair. J Pediatr Surg. 2016 Feb;51(2):240-3. doi: 10.1016/j.jpedsurg.2015.10.069. Epub 2015 Nov 11.

Bhatti TR, Ganapathy K, Huppman AR, Conlin L, Boodhansingh KE, MacMullen C, Becker S, Ernst LM, Adzick NS, Ruchelli ED, Ganguly A, Stanley CA: Histologic and molecular profile of pediatric insulinomas: Evidence of a paternal parent-of-origin effect. J Clin Endocrinol Metab. 2016 Mar;101(3):914-22. doi: 10.1210/jc.2015-2914. Epub 2016 Jan 12.

Mancilla EE, Levine MA, Adzick NS: Outcomes of minimally invasive parathyroidectomy in pediatric patients with primary parathyroidism due to parathyroid adenoma: A single institution experience. J Pediatr Surg. 2016 Feb 4. pii: S0022-3468(16)00060-9. doi: 10.1016/j.jpedsurg.2016.01.018. [Epub ahead of print].

Hawkes CP, Adzick NS, Palladino AA, DeLeon DD: Late presentation of fulminant necrotizing enterocolitis in a child with hyperinsulinism on octreotide therapy. Horm Res Paediatr. 2016 Feb 12. [Epub ahead of print].

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert LM, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Younger gestational age is associated with increased risk of adverse neurodevelopmental outcome during infancy in congenital diaphragmatic hernia. J Pediatr Surg. 2016 Jan 5.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS: Effects of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2016 Jan;51(1):28-32. doi: 10.1016/j.jpedsurg.2015.10.018. Epub 2015 Oct 23.

Kalish JM, Boodhansingh KE, Bhatti TR, Ganguly A, Conlin LK, Becker SA, Givler S, Mighion L, Palladino AA, Adzick NS, DeLeon DD, Stanley CA, Deardorff MA: Persistent congenital hyperinsulinism in children with mosaic paternal 11p uniparental isodisomy and variable features of Beckwith-Wiedemann Syndrome. J Med Genet. 2016 Jan;53(1):53-61. doi: 10.1136/jmedgenet-2015-103394. Epub 2015 Nov 6.

2015

Tulipan NB, Wellons JC, Thom EA, Gupta N, Sutton LN, Burrows PK, Farmer DL, Johnson MP, Walsh W, Tolivaisa S, D’Alton ME, Adzick NS: Prenatal surgery for myelomeningocele and the need for ventricular shunt placement. J Neurosurg Pediatr. 2015 Dec;16(6):613-20. doi: 10.3171/2015.7.PEDS15336. Epub 2015 Sep 15.

Soni S, Moldenhauer JS, Spinner SS, Rendon N, Khalek N, Martinez-Poyer J, Johnson MP, Adzick NS. Chorioamniotic Membrane Separation and Preterm Premature Rupture of Membranes Complicating In Utero Myelomeningocele Repair. Am J Obstet Gynecol. 2015 Dec 12.

Lord K, Radcliffe J, Gallagher PR, Adzick NS, Stanley CA, DeLeon DD: High risk of diabetes and neurobehavioral deficits in individuals with surgically treated hyperinsulinism. J Clin Endocrinol Metab. 2015 Nov;100(11):4133-9. doi: 10.1210/jc.2015-2539. Epub 2015 Sep 1.

Laje P, Pearson EG, Simpao AF, Rehman MA, Sinclair T, Hedrick HL, Adzick NS, Flake AW. The first 100 infant thoracoscopic lobectomies: Observations through the learning curve and comparison to open lobectomy. J Pediatr Surg. 2015 Nov;50(11):1811-6. doi: 10.1016/j.jpedsurg.2015.05.015. Epub 2015 Jun 3.

Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. J Pediatr Surg. 2015 Oct 23.

Danzer E, Thomas NH, Thomas A, Friedman KB, Gerdes M, Koh J, Adzick NS, Johnson MP. Long-term neurofunctional outcome, executive functioning, and behavioral adaptive skills following fetal myelomeningocele surgery. Am J Obstet Gynecol. 2015 Oct 9.

Brock JW III, Carr MC, Adzick NS, Burrows PK, Thomas JC, Thom EA, Howell LJ, Farrell JA, Dabrowiak ME, Farmer DL, Cheng EY, Kropp BP, Caldamone AA, Bulas D, Tolivaisa S, Baskin LS: Bladder function after fetal surgery for myelomeningocele: Results of the MOMS Trial. Pediatrics. 2015 Oct;136(4):e906-13. doi: 10.1542/peds.2015-2114.

Tulipan N, Wellons JC 3rd, Thom EA, Gupta N, Sutton LN, Burrows PK, Farmer D, Walsh W, Johnson MP, Rand L, Tolivaisa S, D'alton ME, Adzick NS; for the MOMS Investigators. Prenatal surgery for myelomeningocele and the need for cerebrospinal fluid shunt placement. J Neurosurg Pediatr. 2015 Sep 15:1-8. [Epub ahead of print]

Brock JW 3rd, Carr MC, Adzick NS, Burrows PK, Thomas JC, Thom EA, Howell LJ, Farrell JA, Dabrowiak ME, Farmer DL, Cheng EY, Kropp BP, Caldamone AA, Bulas DI, Tolivaisa S, Baskin LS; MOMS Investigators. Bladder Function After Fetal Surgery for Myelomeningocele. Pediatrics. 2015 Sep 28. pii: peds.2015-2114. [Epub ahead of print]

Heuer GG, Adzick NS, Sutton LN: Fetal myelomeningocele closure: Technical considerations. Fetal Diagn Ther. 2015;37(3):166-71. doi: 10.1159/000363182. Epub 2014 Aug 28.

Moldenhauer JS, Soni S, Rintoul NE, Spinner SS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Peranteau WH, Rendon N, Koh J, Howell LJ, Heuer GG, Sutton LN, Johnson MP, Adzick NS. Fetal Myelomeningocele Repair: The Post-MOMS Experience at the Children's Hospital of Philadelphia. Fetal Diagn Ther. 2015;37(3):235-40. Epub 2014 Aug 15.

Rychik J, Cohen D, Tran K, Szwast A, Natarajan S, Johnson MP, Moldenhauer JS, Khalek N, Martinez-Poyer J, Flake AW, Hedrick HL, Adzick NS: The role of echocardiography in the intraoperative management of the fetus undergoing myelomeningocele repair. Fetal Diagn Ther. 2015;37(3):172-8. doi: 10.1159/000364863. Epub 2014 Jul 18.

Thawani JP, Nayak NR, Pisapia JM, Tahiri Y, Gebbia J, Adzick NS, Sutton LN, Taylor JA, Heuer GG: Myofascial closure of inclusion cysts following in utero myelomeningocele repair. Pediatr Neurosurg. 2015;50(5):286-90. doi: 10.1159/000433602. Epub 2015 Jul 14.

Copp AJ, Adzick NS, Chitty LS, Fletcher JM, Holmbeck GN, Shaw GM: Spina Bifida. Nature Reviews Disease Primers 1: 20157, 2015.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Herkert L, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Neurodevelopmental outcome at one year of age in congenital diaphragmatic hernia infants not treated with extracorporeal membrane oxygenation. J Pediatr Surg. 2015 Jun;50(6):898-903. doi: 10.1016.

Partridge EA, Peranteau WH, Flake AW, Adzick NS, Hedrick HL. Frequency and complications of inguinal hernia repair in giant omphalocele. J Pediatr Surg. 2015 May 29. pii: S0022-3468(15)00353- PMID: 26078212.

Olive A, Moldenhauer JS, Laje P, Johnson MP, Coleman BG, Victoria T, Flake AW, Adzick NS. Axillary lymphatic malformations: Prenatal evaluation and postnatal outcomes. J Pediatr Surg. 2015 Apr 29. pii: S0022-3468(15)00312-7. doi: 10.1016.

Kovatch KJ, Isaacoff EJ, Prickett KK, Sullivan LM, Adzick NS, Kazahaya K, Bauer AJ, Mostoufi-Moab S: Incidence of pediatric thyroid carcinoma in patients with Graves’ Disease. Horm Res Paediatr. 2015 Apr 15. [Epub ahead of print].

Danzer E, Gerdes M, D’Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL: Patient characteristics are important determinants of short-term neurodevelopmental outcome in children with giant omphalocele. Early Hum Dev. 2015 Mar;91(3):187-93. doi: 10.1016/j.earlhumdev.2014.12.009. Epub 2015 Feb 9.

Laje P, Peranteau WH, Hedrick HL, Flake AW, Johnson MP, Moldenhauer JS, Adzick NS. Ex utero intrapartum treatment (EXIT) in the management of cervical lymphatic malformation. J Pediatr Surg. 2015 Feb;50(2):311-4. doi: 10.1016/j.jpedsurg.2014.11.024. Epub 2014 Nov 10.

Partridge EA, Victoria T, Coleman BG, Martinez-Poyer J, Laje P, Hedrick HL, Flake AW, Adzick NS. Prenatal diagnosis of esophageal bronchus - first report of a rare foregut malformation in utero. J Pediatr Surg. 2015 Feb;50(2):306-10. Epub 2014 Nov 10.

Peranteau WH, Tharakan SJ, Partridge E, Herkert L, Rintoul NE, Flake AW, Adzick NS, Hedrick HL. Systemic hypertension in giant omphalocele: An underappreciated association. J Pediatr Surg. 2015 Feb 23. pii: S0022-3468(15)00131-1. doi: 10.1016.

Partridge EA, Hanna BD, Rintoul NE, Herkert L, Flake AW, Adzick NS, Hedrick HL, Peranteau WH. Brain-type natriuretic peptide levels correlate with pulmonary hypertension and requirement for extracorporeal membrane oxygenation in congenital diaphragmatic hernia. J Pediatr Surg. 2015 Feb;50(2):263-6.

Peranteau WH, Scott Adzick N, Boelig MM, Alan W F, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a single-institution review and predictors of survival in 75 cases. J Pediatr Surg. 2015 Feb;50(2):301-5.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Hoffman C, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Patient characteristics are important determinants of neurodevelopmental outcome during infancy in giant omphalocele. Early Hum Dev. 2015 Feb 9;91(3):187-193.

Partridge EA, Peranteau WH, Rintoul NE, Herkert LM, Flake AW, Adzick NS, Hedrick HL. Timing of repair of congenital diaphragmatic hernia in patients supported by extracorporeal membrane oxygenation (ECMO). J Pediatr Surg. 2015 Feb;50(2):260-2.

2014

Partridge EA, Hanna B, Panitch HB, Rintoul NE, Peranteau WH, Flake AW, Adzick NS, Hedrick HL: Pulmonary hypertension in giant omphalocele infants. J Pediatr Surg. 2014 Dec;49(12):1767-70. doi: 10.1016/j.jpedsurg.2014.09.016. Epub 2014 Nov 14.

Vrecenak JD, Howell LJ, Khalek N, Moldenhauer JS, Johnson MP, Coleman BG, Victoria T, Hedrick HL, Peranteau WH, Flake AW, Adzick NS: Outcomes of prenatally diagnosed chest masses in multigestational pregnancies. Fetal Diagn Ther. 2014;36(4):312-9. doi: 10.1159/000358325. Epub 2014 Nov 5.

Partridge EA, Bridge C, Donaher JG, Herkert L, Grill E, Danzer E, Gerdes M, D’Agnostino JA, Peranteau, WH, Hoffman-Craven CH, Bernbaum JC, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Incidence and factors associated with sensorineural and conductive hearing loss among survivors of congenital diaphragmatic hernia. J Pediatr Surg. 2014 Jun;49(6):890-4; discussion 894. doi: 10.1016/j.jpedsurg.2014.01.019. Epub 2014 Jan 31.

Bebbington MW, Victoria T, Danzer E, Moldenhauer JS, Khalek N, Johnson MP, Hedrick HL, Adzick NS: Comparison of Ultrasound and MRI parameters in predicting survival in isolated left-sided congenital diaphragmatic hernia. Ultrasound Obstet Gynecol. 2014 Jun;43(6):670-4. doi: 10.1002/uog.13271. Epub 2014 May 5.

Jackson EM, Schwartz DM, Zarnow DA, Adzick NS, Johnson MP, Heuer GG, Sutton LN: Intraoperative neurophysiological monitoring in patients undergoing tethered cord surgery after fetal myelomeningocele repair. J Neurosurg Pediatr. 2014 Apr;13(4):355-61. doi: 10.3171/2014.1.PEDS11336. Epub 2014 Feb 7.

Tsai J, Blinman TA, Collins JL, Laje P, Hedrick HL, Adzick NS, Flake AW: The contribution of hiatal hernia to gastroesophageal reflux disease in patients with gastroschisis. J Pediatr Surg. 2014 Mar;49(3):395-8. doi: 10.1016/j.jpedsurg.2013.09.005.

Peranteau WH, Moldenhauer JS, Khalek N, Martinez-Poyer JL, Howell LJ, Johnson MP, Flake AW, Adzick NS, Hedrick HL: Open fetal surgery for central bronchial atresia. Fetal Diagn Ther. 2014;35(2):141-7. doi: 10.1159/000357497. Epub 2014 Jan 23.

Partridge EA, Canning DA, Long C, Peranteau WP, Hedrick HL, Adzick NS, Flake AW: Urologic and anorectal complications of sacrococcygeal teratoma: Prenatal and postnatal predictors. J Pediatr Surg. 2014 Jan;49(1):139-42; discussion 142-3. doi: 10.1016/j.jpedsurg.2013.09.042. Epub 2013 Oct 8.

2013

Laje P, Palladino AA, Bhatti TR, States LJ, Stanley CA, Adzick NS: Pancreatic surgery in Infants with Beckwith-Wiedemann Syndrome and Hyperinsulinism. J Pediatric Surg 48:2511-2516, 2013.

Peranteau WP, Palladino AA, Bhatti TR, States L, Stanley CA, Adzick NS: The surgical management of insulinomas in children. J Pediatr Surg 48:2517-2524, 2013.

Adzick NS: The tribulations and trials of fetal surgery for spina bifida. Proceedings of the American Philosophical Society 157:41-69, 2013.

Kaplan MC, Coleman BG, Shaylor SD, Howell LJ, Horii SC, Adzick NS: Sonographic features of rare posterior neck masses of vascular origin. J Ultrasound Med 32:873-880, 2013.

Danzer E, Gerdes M, D’Agostino JA, Partridge EA, Hoffman-Craven C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Longitudinal neurodevelopmental and neuromotor outcome in congenital diaphragmatic hernia patients in the first 3 years of life. J Perinatology 33:893-898, 2013.

Laje P, Adzick NS: Modified Puestow for the management of chronic pancreatitis in children. J Pediatr Surg 48:2271-2275, 2013.

Laje P, Bhatti TR, Adzick NS: Solid pseudopapillary neoplasm of the pancreas in children: A 15 year experience and identification of a unique immunohistochemical marker. J Pediatr Surg 48:2054-2060, 2013.

Laje P, Howell LJ, Johnson MP, Hedrick HL, Flake AW, Adzick NS: Perinatal management of congenital oropharyngeal tumors: the Ex Utero Intrapartum Treatment (EXIT) approach. J Pediatr Surg 48:2005-2010, 2013.

Danzer E, Gerdes M, D’Agostino J, Partridge E, Hoffman-Craves C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Preschool neurological assessment in congenital diaphragmatic hernia survivors: Outcome and perinatal factors associated with neurodevelopmental impairment. Early Human Development 89:393-400, 2013.

Adzick NS: Fetal surgery for spina bifida: Past, present, future. Sem Pediatric Surgery 22:10-17, 2013.

Adzick NS: Preface to Fetal Surgery – Current Status. Sem Pediatric Surgery 22:1-2, 2013.

Victoria T, Danzer E, Adzick NS: Use of ultrasound and MRI for evaluation of lung volumes in fetuses with isolated congenital diaphragmatic hernia. Sem Pediatric Surgery 22:30-36, 2013.

Laje P, States LJ, Zuang H, Becker SA, Palladino AA, Stanley CA, Adzick NS: The accuracy of PET/CT scan in the diagnosis of the focal form of congenital hyperinsulinism. J Pediatr Surg 48:388-393, 2013.

aje P, Palladino AA, Bhatti TR, States LJ, Stanley CA, Adzick NS: Pancreatic surgery in Infants with Beckwith-Wiedemann Syndrome and Hyperinsulinism. J Pediatric Surg 48:2511-2516, 2013.

2012

Danzer E, Hedrick HL, Rintoul NE, Adzick NS, Panitch HB: Comprehensive assessment of early pulmonary function abnormalities in giant omphalocele survivors. J Pediatr Surg 47:1811-20, 2012.

Victoria T, Bebbington MW, Danzer E, Flake AW, Johnson MP, Adzick NS, Hedrick HL: Use of magnetic resonance imaging in prenatal prognosis of the fetus with isolated left congenital diaphragmatic hernia. Prenatal Diagnosis 32: 715-723, 2012.

Danzer E, Siegle J, D’Agnostino JA, Gerdes M, Hoffman C, Bernbaum J, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Early neurodevelopmental outcome of infants with high-risk fetal lung lesions. Fetal Diagnosis and Therapy 31:210-215, 2012.

Tsai J, Sulkowski J, Adzick NS, Hedrick HL, Flake AW: Patch repair for congenital diaphragmatic hernia: Is there really a problem? J Pediatr Surg 47:637-641, 2012.

Adzick NS: Fetal myelomeningocele repair: Trials and tribulations. J Pediatr Surg 47:273-281, 2012.

Laje P, Johnson MP, Howell LJ, Bebbington MW, Hedrick HL, Flake AW, Adzick NS: Ex Utero Intrapartum Treatment (EXIT) in the management of giant cervical teratomas. J Pediatr Surg 47:1208-16, 2012.

Danzer E, Zarnow D, Gerdes M, D’Agostino JA, Siegle J, Bebbington MW, Flake AW, Adzick NS, Hedrick HL: Abnormal brain development and maturation on MR imaging in congenital diaphragmatic hernia survivors. J Pediatr Surg 47:453-461, 2012.

Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, Flake AW, Adzick NS, Hedrick HL: Fetal MRI calculated lung volumes in the prediction of short-term morbidity in giant omphalocele: Preliminary findings. Fetal Diagnosis and Therapy 31:248-253, 2012.

Laje P, Stanley CA, Palladino AA, Becker SA, Adzick NS: Pancreatic head resection and Roux-en-Y pancreaticojejunostomy for the treatment of the focal form of congenital hyperinsulinism. J Pediatr Surg 47:130-135, 2012.

Danzer E, Johnson MP, Adzick NS: Fetal surgery for myelomeningocele: Progress and perspectives. Dev Med Child Neurol Dev Med Child Neurol. 54:8-14, 2012.

2011

Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick NS, Johnson MP: Preschool neurobehavioral outcome of following fetal myelomeningocele surgery. Fetal Diagnosis and Therapy 30:174-179, 2011.

Danzer E, Adzick NS: Fetal surgery for myelomeningocele: Patient selection, perioperative management, and clinical studies. Fetal Diagnosis and Therapy 30:163-173, 2011.

Bebbington MW, Danzer E, Johnson MP, Adzick NS: Fetal surgery for myelomeningocele. Prenatal Diagnosis 31:689-694, 2011.

Santore MT, Behar BJ, Blinman TA, Adzick NS, Flake AW, Deans KJ: Laparoscopic hepaticoduodenostomy versus open hepatoduodenostomy for reconstruction after resection of choledochal cyst. Journal of Laparoendoscopic & Advanced Surgical Techniques 221:375-8, 2011.

Grant RA, Heuer GG, Carrion GM, Adzick NS, Schwartz ES, Stein SC, Storm PB, Sutton LN,: Morphometric analysis of posterior fossa after in utero myelomeningocele repair. Journal of Neurosurgery: Pediatrics 7:362-8, 2011.

Adzick NS, Thom EA, Spong CY, Brock JW III, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LE, Gupta N, Tulipan NB, D’Alton ME, Farmer DL: A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med 364:993-1004, 2011.

Danzer E, Gerdes M, Bebbington MW, Koh J, Adzick NS, Johnson MP: Fetal myelomeningocele surgery: Preschool functional status using the Functional Independence Measure for Children (WeeFIM). Child's Nervous System 27:1083-8, 2011.

Roybal JL, Moldenhauer JS, Khalek N, Bebbington MW, Johnson MP, Hedrick HL, Adzick NS, Flake AW: Early delivery as an alternative management strategy for selected high-risk sacrococcygeal teratomas. J Pediatr Surg 46:1325-32, 2011.

Danzer E, Zhang L, Radu A, Bebbington MW, Liechty KW, Adzick NS, Flake AW: Amniotic fluid levels of glial fibrillary acidic protein in fetal rats with retinoic acid induced myelomeningocele: A potential marker for spinal cord injury. Am J Ob Gyn 204:178.e1-11, 2011.

Santore MT, Behar BJ, Blinman TA, Doolin EJ, Hedrick HL, Mattei P, Nance ML, Adzick NS, Flake AW: Hepaticoduodenostomy versus hepaticojejunostomy for reconstruction after resection of choledochal cyst. J Pediatr Surg 46:209-213, 2011.

2010

Deprest JA, Flake AW, Gratacos E, Ville Y, Hecher K, Nicolaides K, Johnson MP, Adzick NS, Harrison MR: The making of fetal surgery. Prenatal Diagnosis 30:653-667, 2010.

Roybal JI, Liechty KW, Hedrick HL, Bebbington M, Johnson MP, Coleman B, Adzick NS, Flake AW: Predicting the severity of Congenital High Airway Obstruction Syndrome. J Pediatr Surg 45:1633-1639, 2010.

Danzer E, Finkel R, Gerdes M, Schwartz EM, Rintoul NN, Adzick NS, Johnson MP: The relationship of seizure activity and chronic epilepsy in early infancy and short-term neurodevelopmental outcome following fetal myelomeningocele closure. Neuropediatrics 41:140-143, 2010.

Danzer E, Layne MD, Auber F, Shigu S, Kreiger P, Radu A, Adzick NS, Flake AW: Gastroschisis in mice lacking aortic carboxypeptidase-like protein (ACLP) is associated with a defect in neuromuscular development restricted to the eviscerated intestine: Early characterization and histomorphological assessment. Pediatric Research 68:23-28, 2010.

Laje P, Flake AW, Adzick NS: Prenatal diagnosis and postnatal resection of intra-abdominal intestinal duplications. J Pediatr Surg 45:1554-1558, 2010.

Danzer E, Gerdes M, Bernbaum J, D’Agnostino J, Bebbington M, Siegle J, Hoffman C, Rintoul NE, Flake AW, Adzick NS, Hedrick HL: Neurodevelopmental outcome of infants with congenital diaphragmatic hernia enrolled prospectively in an interdisciplinary follow-up program. J Pediatr Surg 45:1759-1766, 2010.

Wilson RD, Kamerand K, Johnson MP, Flake AW, Bebbington M, Hedrick HL, Adzick NS: Reproductive outcomes in subsequent pregnancies after a pregnancy complicated by maternal-fetal surgery. Am J Ob Gyn 203: 209.e1-6, 2010.

Danzer E, Gerdes M, Bebbington MW, Zarnow DM, Adzick NS, Johnson MP: Preschool neurodevelopmental outcome of children following fetal myelomeningocele closure. Am J Ob Gyn 202: 450; e1-9, 2010.

Laje P, Stanley CA, Adzick NS: Intussusception after pancreatectomy in children: A case series. J Pediatr Surg 45:1496-1499, 2010.

Danzer E, Gerdes M, D'Agostino JA, Bernbaum J, Siegle J, Hoffman C, Rintoul NE, Liechty KW, Flake AW, Adzick NS, Hedrick HL: Prospective, interdisciplinary follow-up of children with prenatally diagnosed giant omphalocele: Short-term neurodevelopmental outcome. J Pediatr Surg 45:718-723, 2010.

Laje P, Halaby L, Adzick NS, Stanley CA: Necrotizing enterocolitis in neonates receiving octreotide for the management of congenital hyperinsulinism. Pediatric Diabetes 11:142-147, 2010.

Adzick NS: Fetal myelomeningocele: Natural history, pathophysiology, and in utero intervention. Sem Fetal Neonatal Med 15:9-15, 2010.

Adzick NS: Open fetal surgery for life-threatening fetal anomalies. Sem Fetal Neonatal Med 15:1-8, 2010.

Danzer E, Finkel RS, Rintoul NE, Bebbington MW, Schwarz ES, Zarnow DM, Adzick NS, Johnson MP: Reversal of hindbrain herniation after maternal-fetal surgery for myelomeningocele subsequently reduces the incidence and severity of brain-stem dysfunction and cranial nerve compression. Neuropediatrics 41:140-3, 2010.

2009

Nallasamy S, Davidson SL, Howell LJ, Macdonald J, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS, Young TL: The effects of fetal surgery on retinopathy of prematurity development. Ophthalmology and Eye Diseases. Ophthalmology and Eye Diseases 1: 13-19, 2009.

Adzick NS: Management of fetal lung lesions. Clinics Perinatology 36:363-376, 2009.

Husler MR, Danzer E, Sutton L, Johnson MP, Bebbington M, Adzick NS, Wilson RW: Prenatal diagnosis and postnatal outcome of spinal defects without Arnold-Chiari II malformation. Prenatal Diagnosis 29:1050-1057, 2009.

Danzer E, Zhang M, Watanabe M, Bebbington MW, Radu A, Liechty KW, Adzick NS, Flake AW: Amniotic fluid levels of glial acidic fibrillary protein in fetal rats with retinoic acid induced myelomeningocele: A potential marker for spinal cord injury. J Am College Surgeons 209:S63, 2009.

Husler MR, Wilson RD, Hori SC, Coleman BG, Bebbington ME, Mann SE, Adzick NS, Johnson MP: When is fetoscopic release of amniotic bands indicated? Review of outcome of cases treated in utero and selection criteria for fetal surgery. Prenatal Diagnosis 29:457-463, 2009.

Danzer E, Ernst L, Rintoul NE, Johnson MP, Adzick NS, Flake AW: In utero meconium passage in fetuses and newborns with myelomeningocele. Journal Neurosurg Ped 3:141-146, 2009.

Victoria T, Kramer SS, Markowitz R, Servaes S, Mong A, Jaramillo D:, Adzick NS Esophageal obstruction and intra-cardiac "mass" in association with omphalocele closure. J Pediatr Surg 44:448-463, 2009.

Danzer E, Gerdes M, Bebbington MW, Sutton LE, Melchionni J, Adzick NS, Johnson MP: Lower extremity neuromotor function and short-term ambulatory potential following in utero myelomeningocele surgery. Fetal Diagnosis and Therapy 25:47-53, 2009.

Wilson RD, Hedrick HL, Flake AW, Johnson MP, Bebbington MW, Mann S, Rychik J, Liechty K, Adzick NS: Sacrococcygeal teratoma: Prenatal surveillance, growth, and pregnancy outcome. Fetal Diagnosis and Therapy 25:15-20, 2009.

2008

Mong A, Johnson AM, Kramer SS, Coleman BG, Hedrick HL, Krieger P, Flake AW, Johnson MP, Wilson RD, Adzick NS, Jaramillo D: Congenital High Airway Obstruction Syndrome: MR/US findings, effect on management, and outcome. Pediatric Radiology 38:1171-1179, 2008.

Danzer E, Adzick NS, Rintoul NE, Zarnow DM, Schwartz ES, Melchionni J, Ernst LM, Sutton LN, Flake AW, Johnson MP: Intradural inclusion cysts following in utero closure of myelomeningocele: Clinical implications and follow-up. Journal of Neurosurgery: Pediatrics 2:406-413, 2008.

Ganesh A, Adzick NS, Foster T, Cucchiaro G: Efficacy of addition of fentanyl to epidural bupivicaine on postoperative analgesia following thoracotomy for lung resection in infants. Anesthesiology 109:90-894, 2008.

Danzer E, Davey MG, Kreiger PA, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL: Fetal tracheal occlusion for severe congenital diaphragmatic hernia: A morphometric study of lung parenchyma and muscularization of pulmonary arterioles. J Pediatr Surg 43:1767-1775, 2008.

Biard J-M, Schwarz U, Davey MG, Danzer E, Johnson MP, Flake AW, Hedrick HL: Main bronchus occlusion for treatment of congenital diaphragmatic hernia in fetal lambs. J Pediatr Surg 43:620-627, 2008.

Tiblad E, Wilson RD, Carr M, Flake AW, Hedrick H, Johnson MP, Bebbington MW, Mann S, Adzick NS: OEIS sequence: A rare congenital anomaly with prenatal evaluation and postnatal outcome in six cases. Prenatal Diagnosis 28:141-147, 2008.

Fichter A, Dornseifer U, Henke J, Schneider KTM, Kovacs L, Biemer E, Bruner J, Adzick NS, Harrison MR, Papadopulos N: Fetal spina bifida repair: Current trends and prospects of intrauterine neurosurgery. Fetal Diagnosis and Therapy 23:271-286, 2008.

Danzer E, Radu A, Robinson LE, Volpe MV, Adzick NS, Flake AW: Morphological analysis of the neuromuscular development of the anorectal unit in fetal rats with retinoic acid induced myelomeningocele. Neuroscience Letters 430:157-62, 2008.

Badillo AT, Hedrick HL, Wilson RD, Danzer E, Bebbington MW, Johnson MP, Liechty KW, Flake AW, Adzick NS: Prenatal ultrasonographic gastrointestinal abnormalities in fetuses with gastroschisis do not correlate with postnatal outcomes. J Pediatr Surg 43:647-653, 2008.

Tsai AY, Liechty KW, Hedrick HL, Bebbington M, Wilson RD, Johnson MP, Howell LJ, Flake AW, Adzick NS: Outcomes following postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions. J Pediatr Surg 43:513-517, 2008.

Peranteau WH, Merchant AM, Hedrick HL, Liechty KW, Howell LJ, Flake AW, Wilson RD, Johnson MP, Bebbington MW, Adzick NS: The prenatal course and postnatal management of peripheral bronchial atresia: Association with congenital cystic adenomatoid malformation of the lung. Fetal Diagnosis and Therapy 24:190-196, 2008.

Danzer E, Davey MG, Kreiger P, Ruchelli ED, Johnson MP, Adzick NS, Flake AW, Hedrick HL: Fetal tracheal occlusion in patients with severe congenital diaphragmatic hernia: A morphologic study of lung architecture and arterial muscularization. J Pediatr Surg 43:1767-1775, 2008.

2007

Bebbington MW, Danzer E, Hedrick HL, Flake AW, Wilson RD, Johnson MP, Adzick NS: Serial measurement of lung head ratio (LHR) does not predict survival in left-sided congenital diaphragmatic hernia (CDH). Ultrasound Obstet Gynecol 30:435, 2007.

Hardy OT, Hernandez-Pampaloni M, Saffer JR, Scheuermann J, Ernst L, Freifelder R, Zhuang Hongming, MacMullen C, Becker S, Adzick NS, Divgi C, Alavi A, Stanley CA: Accuracy of [18F]-fluorodopa PET for diagnosing and localizing focal congenital hyperinsulinism. J Clin Endocrinol Metab 92:4706-4711, 2007.

Husler M, Wilson RD, Rychik J, Bebbington MW, Johnson MP, Mann S, Hedrick HL, Adzick NS: Congenital cystic adenomatoid malformation and conotruncal heart defects: Is there a genetic association? Prenatal Diagnosis 27:1123-1128, 2007.

Hedrick HL, Danzer E, Merchant A, Bebbington MW, Zhao H, Flake AW, Johnson MP, Liechty KW, Howell LJ, Wilson RD, Adzick NS: Liver position and lung-to-head ratio for prediction of extracorporeal oxygenation and survival in isolated left congenital diaphragmatic hernia. Am J Ob Gyn 197:422-423.e1-4, 2007.

Davey MG, Shegu S, Danzer E, Ruchelli E, Adzick NS, Flake AW, Hedrick HL: Pulmonary artery muscularization is reduced by fetal glucocorticoids in lambs with diaphragmatic hernia following tracheal occlusion. Am J Ob Gyn 197:381-382. e1-4, 2007.

Pressey TL, Wilson RD, Kasperski S, Bebbington MW, Adzick NS: Prenatal diagnosis of partial trisomy 1q and Monosomy X in a fetus with a congenital lung lesion and hydrops fetalis. American Journal of Medical Genetics 143:1104-1107, 2007.

Ilagan JG, Wilson RD, Johnson MP, Hedrick HL, Flake AW, Bebbington M, Adzick NS: Pregnancy outcomes following bipolar umbilical cord coagulation for selective termination in complicated monochorionic multiple gestations. Fetal Diagnosis and Therapy 23:145-150, 2007.

Nichol PF, Adzick NS: Gallstone ileus 20 years after Kasai procedure using a stapled anti-reflux valve. J Pediatr Surg 42:264-266, 2007.

Merchant AM, Peranteau W, Wilson RD, Johnson MP, Bebbington M, Hedrick HL, Howell LJ, Flake AW, Adzick NS: Case report: Postnatal chest wall deformities after fetal thoracoamniotic shunting for congenital cystic adenomatoid malformation. Fetal Diagnosis and Therapy 22:435-439, 2007.

Mann S, Wilson RD, Bebbington MW, Adzick NS, Johnson MP: Antenatal diagnosis and management of congenital cystic adenomatoid malformation. Sem Fetal Neonatal Med 12:477-481, 2007.

Peranteau WH, Wilson RW, Liechty KW, Johnson MP, Bebbington MW, Hedrick HL, Flake AW, Adzick NS: The effect of maternal betamethasone on prenatal congenital cystic adenomatoid malformation growth and fetal survival. Fetal Diagnosis and Therapy 22:365-371, 2007.

Netta DA, Wilson RD, Visintainer P, Johnson MP, Hedrick HL, Flake AW, Adzick NS: Gastroschisis: Growth and prenatal surveillance. Fetal Diagnosis and Therapy 27:352-357, 2007.

Wilson RD, Johnson MP, Bebbington M, Flake AW, Hedrick HL, Sutton LN, Adzick NS: Does a myelomeningocele sac compared to no sac increase neonatal morbidity after maternal-fetal surgery? Fetal Diagnosis and Therapy 22:348-351, 2007.

Peranteau WH, Bathaii SM, Pawel B, Hardy O, Alavi A, Stanley CA, Adzick NS: Multiple ectopic lesions of focal islet adenomatosis identified by PET scan in an infant with congenital hyperinsulinism. J Pediatr Surg 42:188-192, 2007.

Danzer E, Johnson MP, Bebbington M, Simon EM, Wilson RD, Bilaniuk LT, Sutton LN, Adzick NS: Fetal head biometry assessed by fetal magnetic resonance imaging following in utero myelomeningocele repair. Fetal Diagnosis and Therapy 22:1-6, 2007.

Danzer E, Kidoo DA, Redden RA, Robinson L, Radu A, Zderic SA, Doolin EJ, Adzick NS, Flake AW: Structural and functional characterization of bladder smooth muscle in fetal rats with retinoic acid induced myelomeningocele. Am J Physiol Renal Physiol 292:F197-206, 2007.

2006

Davey MG, Danzer E, Schwarz U, Robinson L, Shegu S, Adzick NS, Flake AW, Hedrick HL: Prenatal glucocorticoids improves lung morphology and partially restores surfactant mRNA expression in lambs with diaphragmatic hernia undergoing fetal tracheal occlusion. Pediatric Pulmonology 41:1188-1196, 2006.

Danzer E, Radu A, Volpe MV, Adzick NS, Flake AW: Normal neuromuscular development of the lower gastrointestinal tract and anorectum in fetal rats with retinoic acid induced myelomeningocele: Implications for fetal surgery. J American College of Surgeons 203:S36, 2006.

Hussain K, Seppanen M, Nanto-Salonen K, Stanley CA, Adzick NS, Thornton P, Minn H: The diagnosis of ectopic focal hyperinsulinism of infancy with [18F] – DOPA Positron Emission Tomography. J Clin Endocrinol Metab 91:2839-42, 2006.

Howell LJ, Johnson MP, Adzick NS: Creating a state-of-the-art center for fetal diagnosis and treatment: Importance of a multidisciplinary approach. Progress in Pediatric Cardiology 22:121-127, 2006.

Danzer E, Robinson LE, Davey MC, Schwarz U, Volpe M, Adzick NS, Flake AW, Hedrick HL: Tracheal occlusion in fetal rats alters expression of mesenchymal nuclear transcription factors without affecting surfactant protein expression. J Pediatr Surg 41:774-80, 2006.

Davey MG, Schwarz U, Danzer E, Adzick NS, Flake AW, Hedrick HL: Prenatal glucocorticoids and exogenous surfactant therapy improve postnatal lung function in lambs with severe diaphragmatic hernia following prenatal tracheal occlusion. Pediatric Research 60:131-135, 2006.

Johnson MP, Gerdes M, Rintoul N, Howell LJ, Pasquariello P, Melchionni J, Sutton LN, Adzick NS: Maternal-Fetal surgery for myelomeningocele: Neurodevelopmental outcomes at two years of age. American Journal of Obstetrics-Gynecology 194:1145-1152, 2006.

Cucchiaro G, Adzick NS, Rose JB, Maxwell L, Watcha M: A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing Nuss procedure. Anesthesia and Analgesia 103:322-327, 2006.

Suchi M, MacMullen C, Thornton PS, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA: Molecular and immunohistochemical analyses of focal form of congenital hyperinsulinism. Molecular Pathology 19:122-129, 2006.

Kreiger PA, Ruchelli ED, Mahboubi S, Hedrick HL, Adzick NS, Russo PA: Fetal pulmonary malformations: Defining histopathology. American Journal of Surgical Pathology 30:643-649, 2006.

Peranteau WH, Ganguly A, Steinmiller L, Thornton P, Johnson MP, Howell LJ, Adzick NS, Stanley CA: Prenatal diagnosis and postnatal management of diffuse congenital hyperinsulinism: A case report. Fetal Diagnosis and Therapy 21:515-518, 2006.

Liechty KW, Hedrick HL, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Severe pulmonary hypoplasia associated with giant cervical teratoma. J Pediatr Surg 41:230-233, 2006.

Danzer E, Hubbard AM, Hedrick HL, Johnson MP, Wilson RD, Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Diagnosis and characterization of fetal sacrococcygeal teratoma with prenatal MR imaging. Am J Roentgenology 187:W350-356, 2006.

2005

Wilson RW, Hedrick HL, Liechty KW, Flake AW, Johnson MP, Bebbington M, Adzick NS: Cystic adenomatoid malformation of the lung: Review of genetics, prenatal diagnosis, and in utero treatment. American Journal of Medical Genetics 140A:151-155, 2005.

Danzer E, Layne M, Gorman T, Radu A, Adzick NS, Flake A: Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development restricted to the eviscerated intestine. J American College of Surgeons: 201:S52, 2005.

Biard J-M, Johnson MP, Carr M, Wilson RD, Hedrick HL, Pavlock C, Schwarz U, Flake AW, Adzick NS: Long-term outcomes in children treated by prenatal vesicoamniotic shunting for lower urinary tract obstruction (LUTO). Obstetrics and Gynecology 106:503-508, 2005.

Danzer E, Schwarz U, Wehrli S, Radu A, Adzick NS, Flake AW: Retinoic acid induced myelomeningocele in fetal rats: Characterization by histopathological analysis and magnetic resonance imaging. Experimental Neurology 194:467-75, 2005.

Keswani SG, Crombleholme TM, Rychik J, Tian Z, MacKenzie TC, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Lowell LJ, Adzick NS: Impact of continuous intraoperative monitoring on outcomes in open fetal surgery. Fetal Diagnosis and Therapy 20:316-320, 2005.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: The ex utero intrapartum therapy (EXIT) procedure for high risk fetal lung lesions. J Pediatr Surg 40:1038-43, 2005.

Davey MG, Biard JM, Robinson L, Tsai J, Schwarz U, Danzer E, Adzick NS, Flake AW: Surfactant protein expression (mRNA and protein) is increased in the ipsilateral, but not contralateral lungs of fetal sheep with left-sided diaphragmatic hernias. Pediatric Pulmonology 39:359-367, 2005.

Bailey PD, Rose JB, Keswani SG, Adzick NS, Galinkin JL: Does the use of fentanyl in epidural solutions for post-thoracotomy pain management in neonates affect clinical outcome? J Pediatr Surg 40:1118-21, 2005.

Merchant AM, Hedrick HL, Crombleholme TM, Johnson MP, Wilson RD, Howell LJ, Adzick NS, Flake AW: Management of fetal mediastinal teratoma: A report of two cases. J Pediatr Surg 40:228-231, 2005.

Keswani SG, Crombleholme TM, Johnson MP, Flake AW, Hedrick HL, Howell LJ, Wilson RD, Pawel BR, Davis GH, Adzick NS: The prenatal diagnosis and management of mainstem bronchial atresia. Fetal Diagnosis and Therapy 20:74-78, 2005.

2004

Danzer E, Johnson MP, Wilson RD, Flake AW, Hedrick HL, Sutton LN, Adzick NS: Fetal brain biometry following in utero repair of myelomeningocele (MMC). Ultrasound in Obstetrics and Gynecology 24:606-611, 2004.

Mitchell LE, Adzick NS, Melchionne J, Pasquariello PS, Sutton LN, Whitehead AS: Spina bifida. Lancet 364:1885-1895, 2004.

Suchi M, Thornton PS, Adzick NS, MacMullen C, Ganguly A, Stanley CA, Ruchelli ED: Congenital hyperinsulinism: Intraoperative biopsy interpretation can direct the extent of pancreatectomy. American Journal of Surgical Pathology 28:1326-1335, 2004.

Kirsch AJ, Macarek EJ, Chaquor B, Quinn T, Zderic S, Flake AW, Crombleholme TM, Adzick NS, Canning D, Hubbard AM, Rosenbloom, Snyder HM, Howard PS: Molecular response of the bladder to obstruction. Adv Exp Med Biol 539:195-216, 2004.

Danzer E, Wehrli S, Schwarz U, Radu A, Adzick NS, Flake AW: Myelomeningocele in fetal rats induced by retinoic acid: Characterization by magnetic resonance imaging and histopathologic analysis. J Am Coll Surg 199:546, 2004.

Wilson RD, Johnson MP, Flake AW, Crombleholme TM, Hedrick HL, Wilson J, Adzick NS: Maternal reproductive outcomes in pregnancies following an open fetal surgery pregnancy. Am J Ob Gyn 191:1430-1436, 2004.

Biard JM, Wilson RD, Johnson MP, Hedrick HL, Schwarz U, Flake AW, Crombleholme TM, Adzick NS: Prenatally diagnosed giant omphalocele: Short-term and long-term outcomes. Prenatal Diagnosis 24:434-439, 2004.

Rychik J, Tian Z, Ewing S, Cohen D, Howell LJ, Wilson RD, Johnson MP, Hedrick HL, Flake AW, Crombleholme TM, Adzick NS: Acute cardiovascular effects of fetal surgery in the human. Circulation 110:1549-1556, 2004.

Cucchiaro G, Markowitz SD, Kaye R, Adzick NS, Litman RO, Stanley CA, Watcha MF: Blood glucose control during selective arterial stimulation and venous sampling for localization of pancreatic focal adenomatous hyperplasia in anesthetized children. Anesthesia & Analgesia 99:1044-1048, 2004.

Sutton LN, Adzick NS: Fetal surgery for myelomeningocele. Clinical Neurosurgery 51:155-162, 2004.

Wilson RD, Baxter JK, Johnson MP, King M, Kasperski S, Crombleholme TM, Flake AW, Hedrick HL, Howell LJ, Adzick NS: Thoracoamniotic shunts: Fetal treatment of pleural effusions and congenital cystic adenomatoid malformations. Fetal Diagnosis and Therapy 19:413-420, 2004.

Stanley CA, Thornton PS, Ganguly A, MacMillen C, Underwood P, Bhatia P, Steinkrauss L, Kaye R, Ruchelli E, Suchi M, Adzick NS: Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation. Journal of Clinical Endocrinology and Metabolism 89:288-296, 2004.

Hedrick HL, Crombleholme TM, Flake AW, Nance ML, von Allmen D, Howell LJ, Johnson MP, Wilson RD, Adzick NS: Right congenital diaphragmatic hernia: Prenatal assessment and outcome. J Pediatr Surg 39:319-323, 2004.

Adzick NS, Thornton PS, Stanley CA, Kaye RD, Ruchelli E: A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy. J Pediatr Surg 39:270-275, 2004.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: Sacrococcygeal teratoma: Prenatal assessment, fetal intervention, and outcome. J Pediatr Surg 39:430-438, 2004.

2003

Howell LJ, Adzick NS: Establishing a Fetal Therapy Center: Lessons learned. Seminars in Pediatric Surgery 12:209-217, 2003.

Adzick NS, Walsh DS: Myelomeningocele: Prenatal diagnosis, pathophysiology, and management. Seminars in Pediatric Surgery 12:168-174, 2003.

Adzick NS, Kitano Y: Fetal surgery for lung lesions, congenital diaphragmatic hernia, and sacrococcygeal teratoma. Seminars in Pediatric Surgery 12:154-167, 2003.

Sutton LN, Adzick NS, Johnson MP: Fetal surgery for myelomeningocele. Childs Nervous System 19:587-591, 2003.

Adzick NS: Management of fetal lung lesions. Clinics in Perinatology 30:481-492, 2003.

Kitano Y, von Allmen D, Kanai M, Adzick NS, Flake AW: Epinephrine inhibits tracheal occlusion induced lung growth in fetal sheep. Fetal Diagnosis and Therapy 18:333-337, 2003.

Olutoye O, Coleman B, Adzick NS, Flake AW: Abnormal umbilical cord Dopplers may predict impending demise in fetuses with sacrococcygeal teratoma. A report of 2 cases. Fetal Diagnosis and Therapy 18:428-431, 2003.

Lim FY, Crombleholme TM, Flake AW, Hedrick HL, Johnson MP, Adzick NS: Congenital High Airway Obstruction Syndrome (CHAOS): Natural history and management. J Pediatr Surg 38:940-945, 2003.

Keswani SG, Johnson MP, Hori S, Howell LJ, Hedrick HL, Flake AW, Wilson RD, Adzick NS, Crombleholme TM: In utero limb salvage: Fetoscopic release of amniotic bands for threatened limb amputation. J Pediatr Surg 38:848-851, 2003.

Davey MG, Bouchard S, Mendoza JM, Schwarz U, Adzick NS, Hedrick HL, Flake AW: Temporary in utero tracheal occlusion does not restore normal postnatal respiratory function in fetal sheep with severe lung hypoplasia. Journal of Applied Physiology 94:1054-1062, 2003.

Adzick NS, Flake AW, Crombleholme TM: Management of congenital lung lesions. Seminars in Pediatric Surgery 12:147-153, 2003.

Adzick NS: Preface to Fetal Surgery. Seminars in Pediatric Surgery 12:145-146, 2003.

Davey MG, Hedrick HL, Mendoza JM, Doolin EJ, Adzick NS, Flake AW: Measurement of lung parenchymal volume and alveolar surface area in fetal sheep using computer-assisted stereology. Scanning 25:37-44, 2003.

Wilson RD, Johnson MP, Crombleholme TM, Flake AW, Hedrick HL, King M, Howell LJ, Adzick NS: Chorioamniotic membrane separation following open fetal surgery: Pregnancy outcome. Fetal Diagnosis and Therapy 18:314-320, 2003.

Walsh DS, Adzick NS: Fetal surgery for spina bifida. Seminars in Neonatology 8:197-205, 2003.

Hedrick HL, Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD, Adzick NS: The history of fetal diagnosis and treatment: The Children’s Hospital of Philadelphia experience. Fetal Diagnosis and Therapy 18:65-82, 2003.

Tulipan N, Sutton LN, Bruner JP, Cohen BM, Johnson MP, Adzick NS: The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. Pediatric Neurosurgery 38:27-33, 2003.

Johnson MP, Adzick NS, Rintoul N, Crombleholme TM, Flake AW, Howell LJ, Hedrick HL, Wilson RD, Sutton LN: Fetal myelomeningocele repair: Short-term clinical outcomes. Am J Ob Gyn 189:482-487, 2003.

Hirschl RB, Fox W, Glick PL, Greenspan J, Smith K, Thompson A, Adzick NS: A prospective, randomized trial of perfluorocarbon-induced lung growth (PILG) in newborns with congenital diaphragmatic hernia. J Pediatr Surg 38:283-289, 2003.

Bouchard S, Davey MG, Rintoul NE, Walsh DS, Rorke LB, Adzick NS: Correction of hindbrain herniation and anatomy of the vermis following in utero repair of myelomeningocele in sheep. J Pediatr Surg 38:451-458, 2003.

2002

Coleman BG, Howell LJ, Crombleholme TM, Johnson MP, Adzick NS: Fetal therapy: State of the art. Journal of Ultrasound in Medicine 21:1257-1288, 2002.

Davey MG, Hedrick HL, Kanai M, Mendoza JM, Adzick NS, Flake AW: Pulmonary epithelial liquid uptake expressed in relation to alveolar surface area in reduced in fetal lambs following prolonged in utero tracheal occlusion. Pediatric Pulmonology 34:278-286, 2002.

Cohen MS, Rychik J, Bush DM, Tian Z-Y, Howell LJ, Adzick NS, Flake AW, Johnson MJ, Spray TL, Crombleholme TM: Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia. Journal of Pediatrics 141:25-30, 2002.

Midrio P, Silberstein HJ, Bilaniuk LT, Adzick NS, Sutton LN: Prenatal diagnosis of terminal myelocystocele in the fetal surgery era. Neurosurgery 50:1152-5, 2002.

Rintoul N, Sutton LN, Hubbard AM, Cohen B, Melchionni J, Pasquariello PS, Adzick NS: A new look at myelomeningoceles: Functional level, vertebral level, shunting, and the implications for fetal intervention. Pediatrics 109:409-413, 2002.

Crombleholme TM, Coleman BG, Howell LJ, Liechty KW, Johnson MP, Flake AW, Hedrick HL, Adzick NS: Elevated cystic adenomatoid malformation volume ratio (CVR) predicts outcome in prenatal diagnosis of cystic adenomatoid malformation of the lung. J Pediatr Surg 37:331-338, 2002.

Bouchard S, Johnson MP, Flake AW, Adzick NS, Crombleholme TM: The EXIT procedure: Experience and outcome in 31 cases. J Pediatric Surgery 37:418-426, 2002.

MacKenzie TC, Crombleholme TM, Johnson MP, Schnaufer L, Flake AW, Adzick NS: The management of prenatally diagnosed conjoined twins. J Pediatric Surgery 37:303-309, 2002.

2001

MacKenzie TC, Adzick NS: Advances in fetal surgery. J Intensive Care Medicine 16:251-262, 2001.

Bouchard S, Rintoul NE, Davey MG, Walsh DS, Adzick NS: Correction of hindbrain herniation after in utero repair of myelomeningocele in sheep. Surgical Forum 51:419-421, 2001.

Kanai M, Kitano Y, von Allmen D, Davies P, Adzick NS, Flake AW: Fetal tracheal occlusion in the rat model of nitrofen-induced congenital diaphragmatic hernia: Tracheal occlusion reverses the arterial structural abnormality. J Pediatric Surgery 36:839-845, 2001.

Meuli M, Liu Y, Liggitt, Kashani-Saber M, Knauer S, Meuli-Simmen C, Harrison MR, Adzick NS, Reddington J, Heath TD, Debs RJ: Efficient gene expression in skin wound sites following local plasmid injection. Journal of Investigative Dermatology 116:131-135, 2001.

Walsh DW, Adzick NS, Sutton LN, Johnson MP: The rationale for in utero repair of myelomeningocele. Fetal Diagnosis and Therapy 16:312-322, 2001.

MacKenzie TC, Guttenberg ME, Nissenbaum HL, Johnson MP, Adzick NS: A fetal lung lesion consisting of bronchogenic cyst, bronchopulmonary sequestration, and congenital cystic adenomatoid malformation: The missing link? Fetal Diagnosis and Therapy 16:193-195, 2001.

Sutton LN, Sun P, Adzick NS: Fetal neurosurgery. Neurosurgery 48:124-142, 2001.

Bouchard S, Russo P, Adzick NS: Expression of neuropeptides in normal and abnormal appendices. J Pediatr Surg 36:1222-1226, 2001.

Mackenzie TC, Howell LJ, Flake AW, Adzick NS: Management of prenatally diagnosed choledochal cysts. J Pediatr Surg 36:1241-1243, 2001.

Kitano Y, Kanai M, Davies P, von Allmen D, Yang EY, Radu A, Adzick NS, Flake AW: Lung growth induced by prenatal tracheal occlusion and its modifying factors: A study in the rat model of congenital diaphragmatic hernia. J Pediatr Surg 36:251-259, 2001.

2000

Sylvester KG, Nesbit M, Radu A, Herlyn M, Adzick NS, Crombleholme TM: Adenoviral-mediated gene transfer in wound healing: Acute inflammatory response in human skin in the SCID mouse model. Wound Repair and Regeneration 8:36-44, 2000.

Mahle WT, Rychik J, Tian ZY, Cohen MS. Howell LJ, Crombleholme TM, Flake AW, Adzick NS: Echocardiographic evaluation of the fetus with congenital cystic adenomatoid malformation. Ultrasound in Obstetrics and Gynecology 16:620-624, 2000.

Olutoye O, Adzick NS: Fetal surgery for myelomeningocele. Operative Techniques in Plastic and Reconstructive Surgery. 7:82-90, 2000.

Flake AW, Crombleholme TM, Johnson MP, Howell LJ, Adzick NS: Treatment of severe congenital diaphragmatic hernia by fetal tracheal occlusion: Clinical experience with 15 cases. Am J Ob Gyn 183:1059-1066, 2000.

Crombleholme TM, Sylvester K, Flake AW, Adzick NS: Salvage of a fetus with Congenital High Airway Obstruction Syndrome by ex utero intrapartum treatment (EXIT) procedure. Fetal Diagnosis and Therapy 15:280-282, 2000.

Walsh DS, Hutchins GM, Radu A, Adzick NS: Histologic evaluation of fetal spinal cords in myelomeningocele. Surgical Forum 51:440-442, 2000.

Walsh DS, Hubbard AM, Olutoye OO, Crombleholme TM, Flake AW, Johnson MP, Adzick NS: Assessment of fetal lung volumes and liver herniation with magnetic resonance imaging in congenital diaphragmatic hernia. Am J Ob Gyn 183:1067-1069, 2000.

Walsh DS, Adzick NS: Fetal surgical intervention. Amer J Perinatology 17:277-283, 2000.

Lovvorn HN, Savani RC, Ruchelli E, Cass DL, Adzick NS: Serum hyaluronan and its association with unfavorable histology and aggressiveness of heterotransplanted Wilms’ tumor. J Pediatr Surg 35:1070-1078, 2000.

Adzick NS, Nance ML: Medical Progress: Pediatric Surgery. N Engl J Med 342:1651-1657 & 1726-1732, 2000.

Lovvorn HN, Crombleholme TM, Cass DL, Ruchelli E, Morgan MA, Adzick NS: Fetoscopic laser therapy in twin-twin transfusion syndrome with anterior placentation. Ob Gyn (in press).

Kitano Y, Ruchelli E, Weiner S, Adzick NS: Hepatic mesenchymal hamartoma associated with mesenchymal stem villous hyperplasia of the placenta. Fetal Diagnosis and Therapy 15:134-138, 2000.

Liechty KL, Crombleholme TM, Adzick NS: Decreased IL-6 in scarless human fetal repair. Cytokines 12:671-676, 2000.

Liechty KW, Kim HB, Adzick NS, Crombleholme TM: Fetal wound repair in interleukin-10 deficient mice results in scar formation. J Pediatr Surg 35:866-873, 2000.

Kitano Y, Quinn TM, Kanai M, Flake AW, Adzick NS, von Allmen D: Lung growth induced by tracheal occlusion in the sheep is augmented by airway pressurization. J Pediatr Surg 35:216-22, 2000.

Milner R, Kitano Y, Olutoye O, Flake AW, Adzick NS: Radiofrequency thermal ablation (RTA): A potential treatment for hydropic fetuses with a large chest mass. J Pediatr Surg 35:386-89, 2000.

Hubbard AM, Crombleholme TM, Adzick NS, Coleman BG, Meyer JS, Flake AW: Prenatal MRI evaluation of congenital diaphragmatic hernia. Amer J Perinatology 16:407-413, 2000.

Walsh DS, Adzick NS: Fetal intervention: Where we are, where we are going. Contemporary Pediatrics 17:33-55, 2000.

Olutoye O, Coleman B, Hubbard AM, Adzick NS: Prenatal diagnosis and management of congenital lobar emphysema. J Pediatr Surg 35:792-795, 2000.

Carpentieri DF, Guttenberg M, Quinn TM, Adzick NS: Subdiaphragmatic pulmonary sequestration: A case report with review of the literature. Journal Perinatology 1:60-62, 2000.

1999

Kitano Y, Adzick NS: New developments in fetal lung surgery. Current Opinion in Pulmonary Medicine. 5:383-389, 1999.

Sutton LN, Adzick NS, Bilaniuk LT, Johnson MP, Crombleholme TM, Flake AW: Improvement in hindbrain herniation by serial fetal MRI following fetal surgery for myelomeningocele. JAMA 282:1826-1831, 1999.

Yingling C, Meuli M, Meuli-Simmen C, Hoffman K, Adzick NS: Assessment of sensory function in neonatal sheep with somatosensory evoked potentials. I. Methodology and normative data. Pediatr Surg International 15:530-534, 1999.

Yingling CD, Meuli-Simmen C, Meuli M, Timmel GB, Harrison MR, Adzick NS: Experimental fetal neurosurgery: Effects of in utero manipulations on somatosensory evoked potentials. Pediatr Surg International 15:535-539, 1999.

Liechty KW, Herlyn M, Nesbit M, Radu A, Adzick NS, Crombleholme TM: Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing. J Invest Derm 113:375-383, 1999.

Cass DL, Lovvorn HN, Yang EY, Sylvester KG, Adzick NS: Regenerative capabilities of the fetal vascular wall. Surgical Forum 50:468-469, 1999.

Walsh DS, Long P, Olutoye O, Crombleholme TM, Flake AW, Adzick NS: A new minimally invasive technique for fetal tracheal occlusion in congenital diaphragmatic hernia. Surgical Forum 50:504-506, 1999.

Pameijer C, von Allmen D, Rhodes LA, Quinn TM, Adzick NS: Electrocardiographic monitoring in the management of fetal congenital malformations. Surgical Forum 50:503-504, 1999.

Kanai M, Kitano Y, Radu A, Adzick NS, Flake AW, von Allmen D: Effect of prenatal tracheal occlusion on pulmonary arterial structural changes in rats with nitrofen-induced congenital diaphragmatic hernia. Surgical Forum 50:567-568, 1999.

Kitano Y, Davies P, von Allmen D, Adzick NS, Flake AW: Prenatal tracheal occlusion induces lung growth in the hypoplastic lung: A study in the rat model of nitrofen-induced congenital diaphragmatic hernia. Journal of Applied Physiology 87:769-775, 1999.

Howell LJ, Adzick NS: The essentials of a Fetal Treatment Center. Seminars in Perinatology 23:535-540, 1999.

Yang E, Flake AW, Adzick NS: Prospects for fetal gene therapy. Seminars in Perinatology 23:524-534, 1999.

Olutoye O, Adzick NS: Fetal surgery for myelomeningocele. Seminars in Perinatology 23:462-473, 1999.

Kitano Y, Flake AW, Crombleholme TM, Johnson MP, Adzick NS: Open fetal surgery for life-threatening fetal malformations. Seminars in Perinatology 23:448-461, 1999.

Kitano Y, Adzick NS: New developments in fetal lung surgery. Current Opinion in Pediatrics 11:193-199, 1999.

Milner R, Adzick NS: Perinatal management of fetal malformations amenable to surgical correction. Current Opinion in Ob Gyn 11:177-183, 1999.

Yang EY, Kim HB, Shaaban AF, Milner R, Adzick NS, Flake AW: Persistent postnatal transgene expression in both muscle and liver after fetal injection of recombinant adenovirus. J Pediatr Surg 34:766-773, 1999.

Flake AW, Crombleholme TM, Adzick NS: The current status and future potential of fetal intervention: Image is everything. Computerized Med Imaging and Graphics 23:51-57, 1999.

Hubbard AM, Adzick NS, Crombleholme TM, Coleman BG, Howell LJ, Haselgrove JC, Mahboubi S: Congenital chest lesions: Diagnosis and characterization with prenatal MR. Radiology 212:43-48, 1999.

Lovvorn HN, Nance ML, Ferry RJ, Stolte L, Baker L, O’Neill JA, Schnaufer L, Stanley CA, Adzick NS: Congenital hyperinsulinism and the surgeon: Lessons learned over 35 years. J Pediatr Surg 34:786-793, 1999.

Liechty KW, Quinn TM, Cass DL, Crombleholme TM, Flake AW, Adzick NS: Elevated PDGF-B in congenital cystic adenomatoid malformations requiring fetal resection. J Pediatr Surg 34:805-810, 1999.

Quinn TM, Sylvester KG, Kitano Y, Liechty KW, Jarret BP, Adzick NS, Flake AW: Transforming growth factor beta-2 is increased after fetal tracheal ligation. J Pediatr Surg 34:701-705, 1999.

Liechty KW, Crombleholme TM, Weiner S, Bernick B, Flake AW, Adzick NS: Use of the Ex Utero Intrapartum Treatment Procedure for a large fetal neck mass in a twin gestation. Obstet Gyn 93:824-825, 1999.

Liechty KW, Sablich TJ, Adzick NS, Crombleholme TM: Recombinant adenoviral-mediated gene transfer in ischemic impaired wound healing. Wound Repair and Regeneration 7:148-153, 1999.

Adzick NS, Scipione A: Pediatric surgical workload during the past decade: Impact on clinical activity and hospital finance at a Children’s Hospital. J Pediatr Surg 34:133-136, 1999.

Lovvorn HN, Cheung DT, Nimni ME, Perelman N, Estes JM, Adzick NS: Deposition and crosslinking of collagen during fetal and adult sheep wound repair. J Pediatr Surg 34:218-223, 1999.

Yang EY, Cass DL, Sylvester KG, Wilson JM, Adzick NS: Fetal gene therapy: Efficacy, toxicity, and immunologic effects of early gestation recombinant adenovirus. J Pediatr Surg 34:235-241, 1999.

1998

Sylvester KG, Kitano Y, Radu A, Nesbit M, Herlyn M, Adzick NS, Crombleholme TM: Comparison of effects of adenoviral-mediated gene transfer of PDGF-B in diabetic mice and heterozygous controls. Surgical Forum 49:653-4, 1998.

Adzick NS, Sutton LN, Crombleholme TM, Flake AW: Successful fetal surgery for spina bifida. Lancet 350:1675-1676, 1998.

Ferro MM, Milner R, Cannizzaro C, Rodriguez S, Bonifacino G, Zapaterio J, Voto L, Adzick NS: Intrathoracic alimentary tract duplication cysts treated in utero by thoracoamniotic shunting. Fetal Diagnosis and Therapy 13:343-347, 1998.

Kitano Y, Yang EY, von Allmen D, Quinn TM, Adzick NS, Flake AW: Tracheal occlusion in the fetal rat: A new experimental model for the study of accelerated lung growth. J Pediatr Surg 33:1741-1744, 1998.

Liechty KW, Adzick NS: Prospects for fetal therapy for spina bifida. Mental Retard Develop Disabilities 4:291-295, 1998.

Kirsch AJ, Quinn TM, Zderic SA, Duckett JW, Howard P, Flake AW, Crombleholme TM, Adzick NS, Canning DA, Hubbard A, Snyder HM, Macarak EJ: Bladder and renal effects of partial urethral obstruction in the fetal lamb. J Urology 159(5):286-289, 1998.

Liechty KW, Crombleholme TM, Cass DL, Martin B, Adzick NS: Diminished interleukin-8 production in the fetal wound healing response. J Surg Research 77:80-84, 1998.

Kitano Y, Sylvester K, Radu A, Nesbit M, Herlyn M, Adzick NS, Crombleholme TM: Treatment of large excisional healing-impaired wounds in diabetic mice with a replication deficient adenovirus carrying the PDGF-B transgene (AD-CMV-PDGF-B). Surgical Forum 49:651-3, 1998.

Yang EY, Kim HB, Shaaban AF, Milner R, Adzick NS, Flake AW: Fetal intramuscular delivery of recombinant adenovirus results in persistent postnatal transgene expression in both muscle and liver. Surgical Forum 49:368-9, 1998.

Kitano Y, von Allmen D, Yang EY, Quinn TM, Kanai M, Adzick NS, Flake AW: Prenatal tracheal occlusion enhances lung growth in the nitrofen-induced rat CDH model. Surgical Forum 49:587-9, 1998.

Lovvorn HN, Crombleholme TM, Drott H, Flake AW, Adzick NS: Maternal colloid osmotic pressure after fetal surgery. Surgical Forum 49:481-3, 1998.

Adzick NS, Harrison MR, Crombleholme TM, Flake AW, Howell LJ: Fetal lung lesions: Management and outcome. Am J Obstet Gynecol 179:884-9, 1998.

Namba R, Meuli M, Sullivan KM, Le A, Adzick NS: The spontaneous repair of superficial articular cartilage defects in a fetal lamb model. J Bone Joint Surg 80A:4-10, 1998.

Yang EY, Adzick NS: Fetoscopy. Seminars in Laparoscopic Surgery 5:31-9, 1998.

Hubbard AM, Crombleholme TM, Adzick NS: Prenatal MRI evaluation of giant neck masses in preparation for the fetal EXIT procedure. Amer Journal Perinatology 15:253-257, 1998.

Lovvorn HN, Cass DL, Sylvester KG, Crombleholme TM, Adzick NS, Savani RC: Hyaluronan receptor expression increases in fetal excisional skin wounds and correlates with fibroplasia. J Pediatr Surg 33:1062-1070, 1998.

Sylvester KG, Rasanen J, Kitano Y, Flake AW, Crombleholme TM, Adzick NS: Fetal tracheal occlusion reverses the high vascular impedance in diaphragmatic hernia. J Pediatr Surg 33:1071-1075, 1998.

Cass DL, Quinn TM, Yang EY, Liechty KW, Crombleholme TM, Flake AW, Adzick NS: Increased cell proliferation and decreased apoptosis characterizes congenital cystic adenomatoid malformation. J Pediatr Surg 33:1043-1047, 1998.

Stelnicki EJ, Komuves LG, Kwong AO, Holmes D, Klein P, Rozenfeld S, Lawrence HJ, Adzick NS, Harrison MR, Largman C: HOX homeobox genes exhibit spatial and temporal changes in expression during human skin development. J Invest Derm 110:110-115, 1998.

Quinn TM, Hubbard AM, Adzick NS: Prenatal magnetic resonance imaging enhances prenatal diagnosis. J Pediatr Surg 33:553-558, 1998.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M, Adzick NS: Epithelial integrin expression is upregulated rapidly in human fetal wound repair. J Pediatr Surg 33:312-316, 1998.

Graf JL, Housley HT, Albanese CT, Adzick NS, Harrison MR: A surprising histologic evolution of preterm sacrococcygeal teratomas. J Pediatr Surg 33:177-179, 1998.

1997

Bruch S, Adzick NS, Reiss R, Harrison MR: Prenatal therapy for pericardial teratoma. J Pediatr Surg 32:1113-1115, 1997.

Liechty KW, Crombleholme TM, Sylvester KG, Lovvorn HN, Kitano Y, Cass DL, Adzick NS: Differential IL-6 production by fetal vs. adult fibroblasts. Surgical Forum 47:707-709, 1997.

Quinn TM, Kirsch AJ, Zderic SA, Duckett JW, Howard P, Flake AW, Adzick NS, Canning DA, Snyder HM, Macarak EJ: Renal effects of partial bladder outlet obstruction in the fetal lamb. Surgical Forum 47:764-766, 1997.

Stelnicki EJ, Komuves LG, Holmes D, Clavin W, Harrison MR, Adzick NS, Largman C: The human homeobox genes MSX-1, MSX-2, and MOX-1 are differentially expressed in the dermis and epidermis in fetal and adult skin. Differentiation 62:33-41, 1997.

Liechty KW, Crombleholme TM. Flake AW, Morgan MA, Kurth CD, Hubbard AM, Adzick NS: Intrapartum airway management for giant fetal neck masses: The EXIT procedure (Ex Utero Intrapartum Treatment). Am J Ob Gyn 177:870-874, 1997.

Quinn TA, Adzick NS: Fetal surgery. Obstetr Gyn Clin North America. 24:143-157, 1997.

Yang EY, Cass DL, Sylvester KG, Flake AW, Wilson JM, Adzick NS: Liver-directed fetal gene therapy using recombinant adenoviral vectors: Successful readministration in mid-gestation sheep fetuses. Surgical Forum 48:464-467, 1997.

Sylvester KG, Rasanen J, Kitano Y, Flake AW, Crombleholme TM, Adzick NS: Fetal tracheal occlusion reverses the high vascular impedance in diaphragmatic hernia. Surgical Forum 48:649-651, 1997.

Cass DL, Yang EY, Liechty KW, Quinn TM, Crombleholme TM, Flake AW, Adzick NS: Increased cell proliferation and decreased apoptosis in congenital cystic adenomatoid malformation: Insights into pathogenesis. Surgical Forum 48:659-661, 1997.

Meuli-Simmen C, Meuli M, Adzick NS, Ursell PC, Harrison MR: Latissimus dorsi flap procedure to cover myelomeningocele in utero: A feasibility study in human fetuses. J Pediatr Surg 32:1154-1156, 1997.

Hubbard AM, Adzick NS, Crombleholme TM, Haselgrove JC: Left congenital diaphragmatic hernia: Value of prenatal MR imaging in preparation for fetal surgery. Radiology 203:636-640, 1997.

Cass DL, Meuli M, Adzick NS: Scar Wars: Implications of fetal wound healing for the pediatric burn patient. Pediatr Surg International 12: 484-489, 1997.

Graf JL, Bealer JF, Gibbs DL, Adzick NS, Harrison MR: Chorioamniotic membrane separation: A potentially lethal finding. Fetal Diagnosis and Therapy 12:81-84, 1997.

Sylvester KG, Yang EY, Cass DL, Crombleholme TM, Adzick NS: Fetoscopic gene therapy for congenital lung disease. J Pediatr Surg 32:964-969, 1997.

Cass DL, Crombleholme TM, Howell LJ, Stafford PW, Adzick NS: Cystic lung lesions with systemic arterial blood supply: A hybrid of congenital cystic adenomatoid malformation and bronchopulmonary sequestration. J Pediatr Surg 32:986-990, 1997.

Cha I, Adzick NS, Harrison MR, Finkbeiner WE: Fetal congenital cystic adenomatoid malformation of the lung: A clinicopathologic study of eleven cases. American J Surg Path 21:537-544, 1997.

Cass DL, Sylvester KG, Yang EY, Crombleholme TM, Adzick NS: Myofibroblast persistence in fetal sheep wounds is associated with scar formation. J Pediatr Surg 32:1017-1022, 1997.

Stelnicki EJ, Bullard KM, Harrison MR, Cass DL, Adzick NS: A new in vivo model for the study of fetal wound healing. Ann Plast Surg 39:374-80, 1997.

Harrison MR, Adzick NS, Bullard KM, Farrell JA, Howell LJ, Rosen MA, Sola A, Goldberg JD, Filly RA: In utero repair of congenital diaphragmatic hernia: A prospective trial. J Pediatr Surg 32:1637-1642, 1997.

Bullard KM, Cass DL, Banda MJ, Adzick NS: TGF-beta1 decreases collagenase in healing human fetal skin. J Pediatr Surg 32:1023-1027, 1997.

Bullard K, Adzick NS, Harrison MR: Mediastinal window: A minimally invasive approach to aortopexy. J Pediatr Surg 32:680-681, 1997.

Mychaliska G, Bealer J, Graf J, Adzick NS, Harrison MR: Operating on placental support: The Ex Utero Intrapartum Treatment (EXIT) procedure. J Pediatr Surg 32:327-331, 1997.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Longaker MT, Adzick NS: Wound size and gestational age modulate scar formation in fetal wound repair. J Pediatr Surg 32:411-415, 1997.

West DC, Shaw DM, Lorenz P, Adzick NS, Longaker MT: Fibrotic healing of adult and late gestation fetal wounds correlates with increased hyaluronidase activity and removal of hyaluronan. Int J Biochem Cell Biol 29: 201-210, 1997.

Gibbs DL, Rice HE, Farrell JA, Adzick NS, Harrison MR: Familial congenital diaphragmatic hernia: An autosomal recessive syndrome with a poor prognosis. J Pediatr Surg 32:366-368, 1997.

Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Midgestational sciatic nerve transection in fetal sheep results in absent nerve regeneration and neurogenic muscle atrophy. Plast Reconstr Surg 99:486-492, 1997.

Adzick NS, Crombleholme TM, Morgan MA, Quinn TM: A rapidly growing fetal teratoma. Lancet 349:538, 1997.

Meuli M, Meuli-Simmen C, Hutchins GM, Seller MJ, Harrison MR, Adzick NS: The spinal cord lesion in human fetuses with myelomeningocele: Implications for fetal surgery. J Pediatr Surg 32:448-452, 1997.

Vanderwall KJ, Kohl T, Adzick NS, Harrison MR, Silverman NH: Fetal diaphragmatic hernia: Echocardiography and clinical outcome. J Pediatr Surg 32:223-226, 1997.

Bullard KM, Sonne J, Hawgood S, Harrison MR, Adzick NS: Tracheal ligation increases cell proliferation but decreases surfactant protein production in fetal murine lungs in vitro. J Pediatr Surg 32:207-213, 1997.

Graf J, Vanderwall K, Adzick NS, Harrison MR: Nitroglycerin attenuates the bowel damage of necrotizing enterocolitis in a rabbit model. J Pediatr Surg 32:283-286, 1997.

Graf J, Gibbs D, Adzick NS, Harrison MR: Fetal hydrops following in utero tracheal occlusion. J Pediatr Surg 32:214-216, 1997.

1996

Graf J, Gibbs D, Adzick NS, Harrison MR: Fetal hydrops following in utero tracheal occlusion. J Pediatr Surg 32:214-216, 1997.

Gallo R, Kim C, Kokenyesi R, Adzick NS, Bernfield M: Syndecans-1 and -4 are locally and distinctly induced during wound repair of neonatal but not fetal skin. J Invest Derm 107:676-683, 1996.

Hoffman KM, Timmel GB, Meuli-Simmen C, Meuli M, Yingling CD, Adzick NS: Experimental fetal neurosurgery: The normal neurology of neonatal lambs and abnormal findings after in utero manipulation. Contemporary Topics in Laboratory Animal Medicine 35:53-56, 1996.

Cass DL, Bullard KM, Sylvester KG, Yang EY, Sheppard D, Herlyn M, Adzick NS: Epithelial integrin expression is rapidly upregulated in human fetal wound repair. Surgical Forum 47:765-767, 1996.

Bullard KM, Cass DL, Banda MJ, Adzick NS: TGF-beta1 decreases collagenase in healing human fetal skin. Surgical Forum 47:762-765, 1996.

Skarsgard ED, Meuli M, VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Fetal endoscopic tracheal occlusion ("Fetendo-Plug") for congenital diaphragmatic hernia. J Pediatr Surg 31:1335-1338, 1996.

Meuli-Simmen C, Meuli M, Hutchins GM, Yingling CD, Timmel GB, Harrison MR, Adzick NS: The fetal spinal cord does not regenerate after in utero transection in a large mammalian model. Neurosurgery 39:555-561, 1996.

Bullard KM, Adzick NS: Pediatric thoracoscopy: A new vista. Pediatric Pulmonology 22:129-135,1996.

Harrison MR, Adzick NS, Flake AW, Vanderwall KJ, Bealer JF, Howell LJ, Farrell JA, Filly RA, Rosen MA, Sola A, Goldberg JD: Correction of congenital diaphragmatic hernia in utero VIII: Response of the hypoplastic lung to tracheal occlusion. J Pediatr Surg 31:1339-1348, 1996.

Vanderwall KJ, Bruch SW, Szabo Z, Meuli M, Adzick NS, Harrison MR: Fetal endoscopic (‘Fetendo”) tracheal clip. J Pediatr Surg 31:1101-1104, 1996.

Bealer JF, Graf J, Bruch SW, Adzick NS, Harrison MR: Gastroschisis increases small bowel nitric oxide synthase activity. J Pediatr Surg 31:1043-1046, 1996.

Hedrick MH, Rice HE, Vanderwall KJ, Adzick NS, Harrison MR, Siebert J, Hoffman WY, Longaker MT: Delayed in utero repair of surgically created fetal cleft lip and palate, Plast Reconstr Surg 97:900-907, 1996.

Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hutchins GM, Timmel GB, Harrison MR, Adzick NS: In utero repair of experimental myelomeningocele spares neurologic function at birth. J Pediatr Surg 31:397-402, 1996.

Bruch SW, Adzick NS, Goldstein RB, Harrison MR: Challenging the embryogenesis of cloacal exstrophy. J Pediatr Surg 31:768-770, 1996.

Metkus AP, Filly RA, Stringer MD, Harrison MR, Adzick NS: Sonographic predictors of survival in fetal diaphragmatic hernia. J Pediatr Surg 31:148-152, 1996.

Lin RY, Adzick NS: The role of the fetal fibroblast and transforming growth factor beta in a model of human fetal wound repair. Seminars Pediatr Surg 5:165-174, 1996.

1995

Bealer JF, Skarsgard ED, Hedrick MH, Meuli M, VanderWall KJ, Flake AW, Adzick NS, Harrison MR: The "PLUG" odyssey: Adventures in experimental tracheal occlusion. J Pediatr Surg 30:361-365, 1995.

Bealer JF, Skarsgard ED, Toth TL, Gibbs D, Adzick NS, Harrison MR: Cervical sonomicrometry detects preterm labor. Surgical Forum 46:557-560, 1995.

Siebert JW, Sung JJ, Zirn J, Kamino H, Hedrick MH, Adzick NS, Gold LI, Longaker MT: Immunohistochemical localization of transforming growth factor beta isoforms during fetal wound healing. Surgical Forum 46:646-648, 1995.

Meuli-Simmen C, Meuli M, Yingling CD, Eiman T, Timmel GB, Buncke HJ, Linenweaver W, Harrison MR, Adzick NS: Failure of the fetal sciatic nerve to regenerate at midgestation. Surgical Forum 46:689-692, 1995.

Meuli M, Liu Y, Liggit D, Meuli-Simmen C, Knauer S, Harrison MR, Adzick NS, Debs RJ: Cutaneous gene expression after local DNA delivery. Surgical Forum 46:701-702, 1995.

Meuli M, Meuli-Simmen C, Hutchins GM, Yingling CD, Hoffman KM, Harrison MR, Adzick NS: In utero surgery rescues neurologic function at birth in sheep with spina bifida. Nature Medicine 1:342-347, 1995.

Adzick NS, Harrison MR: The Unborn Surgical Patient. Current Problems in Obstetrics, Gynecology, and Fertility, Mosby-Year Book; 6:173-220, 1995.

Lorenz HP, Lin RY, Longaker MT, Whitby DJ, Adzick NS: The fetal fibroblast: The effector cell for scarless fetal skin repair. Plast Reconstr Surg 96:1251-1261, 1995.

Meuli-Simmen C, Meuli M, Hutchins GM, Harrison MR, Buncke HJ, Sullivan KM, Adzick NS: Fetal reconstructive surgery: Experimental use of latissimus dorsi flap to correct myelomeningocele in utero. Plastic Reconstructive Surgery 96:1007-1011, 1995.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Exogenous transforming growth factor beta amplifies its own expression and induces scar formation in a model of human fetal skin repair. Ann Surg 222:146-154, 1995.

Bealer JF, Raisanen J, Skarsgard ED, Long SR, Wong K, Filly RA, Adzick NS, Harrison MR: The incidence and spectrum of neurologic injury following open fetal surgery for congenital anomalies. J Pediatr Surg 30:1150-1154, 1995.

Skarsgard ED, Bealer JF, Meuli M, Adzick NS, Harrison MR: Fetal endoscopic surgery: The relationship between insufflating pressure and the placental circulation. J Pediatr Surg 30:1165-1168, 1995.

Lin RY, Argenta PA, Sullivan KM, Adzick NS: Diagnostic and prognostic role of basic fibroblast growth factor in the urine of Wilms' tumor patients. Clinical Cancer Research 1:327-331, 1995.

VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Cyclic GMP relaxes the internal anal sphincter in Hirschsprung's disease. J Pediatric Surg 30:1013-1016, 1995.

Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: Creation of myelomeningocele in utero: A model of functional damage from spinal cord exposure in fetal sheep. J Pediatr Surg 30:1028-1033, 1995.

Sullivan KM, MacGillivray TE, Meuli M, Adzick NS: An adult-fetal skin interface heals without scar formation in sheep. Surgery 118:82-86, 1995.

Bootstaylor BS, Filly RA, Harrison MR, Adzick NS: Prenatal sonographic predictors of liver herniation in congenital diaphragmatic hernia. J Ultrasound Med 14:515-520, 1995.

Stringer MD, Goldstein RB, Filly RA, Howell LJ, Sola A, Adzick NS, Harrison MR: Fetal diaphragmatic hernia without visceral herniation. J Pediatr Surg 30:1264-1266, 1995.

Stringer MD, McKenna KM, Goldstein RB, Filly RA, Adzick NS, Harrison MR: Prenatal diagnosis of esophageal atresia. J Pediatr Surg 30:1258-1263, 1995.

Meuli M, Lorenz HP, Hedrick MH, Sullivan KM, Harrison MR, Adzick NS: Scar formation in the fetal alimentary tract. J Pediatr Surg 30:392-395, 1995.

Sullivan KM, Lorenz HP, Adzick NS: A model of human fetal skin repair is deficient in transforming growth factor beta. J Pediatr Surg 30:198-203, 1995.

Lin RY, Argenta PA, Sullivan KM, Stern R, Adzick NS: Urinary hyaluronic acid is a Wilms' tumor marker. J Pediatr Surg 30:304-308, 1995.

Metkus AP, Harrison MR, Sola A, Adzick NS: Cost per anomaly (CPA): What does a diaphragmatic hernia cost? J Pediatr Surg 30:226-230, 1995.

1994

Hedrick MH, Estes JM, Sullivan KM, Bealer JF, Kitterman JA, Flake AW, Adzick NS, Harrison MR: Plug the lung until it grows (PLUG): A new method to treat congenital diaphragmatic hernia in the fetus. J Pediatr Surg 29:612-617, 1994.

Argenta PA, Lin RY, Sullivan KM, Adzick NS: Urinary basic fibroblast growth factor is a Wilms' tumor marker. Surgical Forum 45:789-791, 1994.

Meuli M, Meuli-Simmen C, Yingling CD, Hoffman KB, Harrison MR, Adzick NS: A new model of myelomeningocele: Studies in the fetal lamb. Surgical Forum 45:587-589, 1994.

VanderWall KJ, Bealer JF, Adzick NS, Harrison MR: Cyclic GMP relaxes the internal anal sphincter in Hirschsprung's disease. Surgical Forum 45:657-659, 1994.

West DC, Shaw DM, Lorenz HP, Adzick NS, Longaker MT: Hyaluronidase activity in fetal and adult wounds. Surgical Forum 45:753-754, 1994.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Species-specific in situ hybridization demonstrates that the human fetal fibroblast modulates scarless repair. Surgical Forum 45:659-662, 1994.

Sullivan KM, MacGillivray TE, Meuli M, Adzick NS: An adult-fetal skin interface heals without scar formation in sheep. Surgical Forum 45:662-664, 1994.

Lin RY, Sullivan KM, Argenta PA, Lorenz HP, Adzick NS: Scarless human fetal skin repair is intrinsic to the fetal fibroblast and occurs in the absence of an inflammatory response: In situ hybridization and immunohistochemical studies. Wound Repair and Regeneration 2:297-305, 1994.

Babcook CJ, Hedrick MH, Filly RA, Goldstein RB, Callen PW, Harrison MR, Adzick NS: Gastroschisis: Can sonography of the fetal bowel accurately predict postnatal outcome? J Ultrasound in Med 13:701-6, 1994.

Adzick NS: Fetal cystic adenomatoid malformation. Seminars Thoracic Cardiovasc Surg 6:247-252, 1994.

Sullivan KM, Adzick NS: Fetal surgery. Clin Obstet Gyn 37:355-371, 1994.

Adzick NS, Harrison MR: Fetal surgical therapy. Lancet 343:897-902, 1994.

Evans MI, Adzick NS, Johnson MP, Flake AW, Quintero R, Harrison MR: Fetal therapy - 1994. Curr Opinion Ob Gyn 6:58-64, 1994.

Harrison MR, Adzick NS, Estes JM, Howell LJ: A prospective study of the outcome for fetuses with diaphragmatic hernia. JAMA 271(5):382-384, 1994.

Adzick NS, Lorenz HP: Cells, matrix, growth factors, and the surgeon: The biology of scarless fetal wound repair. Ann Surg 220:10-18, 1994.

Estes JM, Vande Berg JS, Adzick NS, MacGillivray TE, Desmouliére A, Gabbiani G: Phenotypic and functional features of myofibroblasts in fetal wounds. Differentiation, 56:173-181,1994.

Bealer JF, Natuzzi ES, Buscher C, Ursell PC, Flake AW, Adzick NS, Harrison MR: Nitric oxide synthase is deficient in the aganglionic colon of patients with Hirschsprung's disease. Pediatrics 93:647-651, 1994.

Bealer JF, Natuzzi ES, Flake AW, Adzick NS, Harrison MR: The effect of nitric oxide on the colonic smooth muscle of patients with Hirschsprung's disease. J Pediatr Surg 29:1025-1029, 1994.

Hill AC, Adzick NS, Stevens MB, Mori H, Husseini W, Heymann MA: Fetal lamb pulmonary hypoplasia: Pulmonary vascular and myocardial abnormalities. Ann Thor Surg 57:946-951, 1994.

Sullivan KM, Hawgood S, Flake AW, Harrison MR, Adzick NS: Amniotic fluid phospholipid analysis in the congenital diaphragmatic hernia fetus. J Pediatr Surg 29:1020-1024, 1994.

MacGillivray TE, Jennings RW, Rudolph AM, Ring EJ, Adzick NS, Harrison MR: Vascular changes with in utero correction of diaphragmatic hernia. J Pediatr Surg 29:992-996, 1994.

Longaker MT, Whitby DJ, Ferguson MWJ, Harrison MR, Adzick NS: Adult skin in the fetal environment heals with scar formation. Ann Surg 219:65-72, 1994.

Rice HE, Estes JM, Hedrick MH, Bealer JF, Harrison MR, Adzick NS: Congenital cystic adenomatoid malformation: A sheep model of fetal hydrops. J Pediatr Surg 29(5):692-696, 1994.

Hedrick MH, Martinez-Ferro M, Filly RA, Flake AW, Harrison MR, Adzick NS: Prenatal diagnosis of congenital high airway obstruction (CHAOS): Potential for perinatal intervention. J Pediatr Surg 29:271-274, 1994.

MacGillivray TE, Adzick NS: Biliary atresia begins before birth. Pediatr Surg International 9:116-117, 1994.

1993

Hedrick MH, Jennings RW, MacGillivray TE, Rice HE, Flake AW, Adzick NS, Harrison MR: Chronic fetal vascular access: A new approach to the care of the fetal patient. Lancet 342:1086-7, 1993.

Qian JJ, Duncan BW, Adzick NS, Bhatnagar RS: Regulation of prolyl hydroxylase by ascorbic acid is mediated by polyADP-ribose synthesis. Cellular and Molecular Biol Res 39:525-533, 1993.

Kaban LB, Dodson TB, Stern M, Umeda H, Longaker MT, Adzick NS: Fetal cleft lip repair in rabbits: Long-term clinical and cephalometric results. Cleft Palate Craniofacial J 30:12-18, 1993.

Hedrick MH, Estes JM, Sullivan KM, Bealer JF, Flake AW, Adzick NS, Harrison MR: Plug the lung until it grows (PLUG): A new method to treat congenital diaphragmatic hernia in the fetus. Surgical Forum 44:644-646, 1993.

Sullivan KM, Lorenz HP, Adzick NS: The role of transforming growth factor beta in human fetal wound healing. Surgical Forum 44:625-627, 1993.

Chang J, Longaker MT, Lorenz HP, Roberts AB, Harrison MR, Adzick NS, Banda MJ: Fetal and adult sheep fibroblast TGF-ß1 gene expression in vitro: Effects of hypoxia and gestational age. Surgical Forum 44:720-722, 1993.

Adzick NS, Harrison MR: Fetal surgical techniques. Seminars in Pediatr Surg 2:136-142, 1993.

Harrison MR, Adzick NS, Flake AW: Congenital diaphragmatic hernia: An unsolved problem. Seminars Pediatr Surg 2:109-112, 1993.

Adzick NS: Fetal thoracic lesions. Seminars Pediatr Surg 2:103-108, 1993.

Rice HE, Adzick NS: Prenatal diagnosis: Essentials for the pediatric surgeon. Seminars Pediatr Surgery 2:84-91, 1993.

Howell LJ, Adzick NS, Harrison MR: The Fetal Treatment Center. Seminars Pediatr Surg 2:143-146, 1993.

Adzick NS and Harrison MR: The developmental pathophysiology of surgical disease. Seminars Pediatr Surg 2:92-102, 1993.

Adzick NS: Preface to The Fetus as a Surgical Patient. Seminars Pediatr Surg 2:82-83, 1993.

MacGillivray TE, Harrison MR, Goldstein RB, Adzick NS: Disappearing fetal lung lesions. J Pediatr Surg 28:1321-1325, 1993.

Adzick NS, Harrison MR: Management of the fetus with a cystic adenoma Fetoscopic gene therapy for congenital lung disease icd malformation. World J Surgery 17:342-349, 1993.

Lorenz HP, Adzick NS: Scarless skin wound repair in the fetus. West J Med 159:350-355, 1993.

Jennings RW, La Quaglia MP, Hendren WH, Adzick NS: Fetal neuroblastoma: Prenatal diagnosis and natural history. J Pediatr Surg 28:1168-1174, 1993.

Estes JM, Adzick NS, Longaker MT, Harrison MR, Stern R: Hyaluronate metabolism undergoes ontogenetic transition during fetal development: Implications for scarless wound healing. J Pediatr Surg 28:1227-1231, 1993.

Harrison MR, Adzick NS, Flake AW, Jennings RW, Estes JM, MacGillivray TE, Chueh JT, Golbus MS, Filly RA, Goldstein RB, Howell LJ: Correction of congenital diaphragmatic hernia in utero: VI. Hard-earned lessons. J Pediatr Surg 28:1411-1418, 1993.

Freund RM, Siebert JW, Cabrera J, Longaker MT, Eidelman Y, Adzick NS, Garg HG: Serial quantitation of hyaluronan and sulfated glycosaminoglycans in fetal sheep skin. Biochem Mol Biol Int 29:773-784, 1993.

Harrison MR, Adzick NS, Flake AW, Jennings RW: The CDH two-step: A dance of necessity. J Pediatr Surg 28:813-816, 1993.

Lorenz HP, Adzick NS, Harrison MR: Open human fetal surgery. Advances in Surgery 26:259-273, 1993.

Adzick NS, Harrison MR, Flake AW, Howell LJ, Golbus MS, Filly RA: Fetal surgery for cystic adenomatoid malformation of the lung. J Pediatr Surg 28:806-812, 1993.

Lorenz HP, Whitby DJ, Longaker MT, Adzick NS: Fetal wound healing: The ontogeny of scar formation in the non-human primate. Ann Surg 217:391-6, 1993.

Jennings RW, Adzick NS, Longaker MT, Harrison MR: Radiotelemetric fetal monitoring during and after open fetal surgery. Surg Gyn Obstet 176:59-64, 1993.

1992

Lorenz HP, Longaker MT, Whitby DJ, Harrison MR, Adzick NS: Scarless fetal skin repair is intrinsic to the fetal fibroblast. Surgical Forum 43:694-6, 1992.

Jennings RW, MacGillivary TE, Rudolph AM, Ring EJ, Adzick NS, Harrison MR: Vascular considerations in correction of congenital diaphragmatic hernia. Surgical Forum 43:629-31, 1992.

Hedrick MH, Jennings RW, MacGillivray TE, Flake AW, Lorenz HP, Estes JM, Roberts LJ, Adzick NS, Harrison MR: Endoscopic catheterization of placental vessels for chronic fetal vascular access. Surgical Forum 43:504-5, 1992.

Adzick NS, Harrison MR: Fetal surgery: A new frontier. Postgraduate General Surgery 4:48-56, 1992.

Lorenz HP, Adzick NS, Longaker MT, Stern R: Scarless fetal wound repair: A review. Advances in Plastic and Reconstructive Surgery 9:83-101, 1992.

Adzick NS, Longaker MT: Scarless fetal healing: Therapeutic implications. Ann Surg 215(1):3-6, 1992.

Duncan BW, Adzick NS, Moelleken BRW, Chua J, Bradley SM, Longaker MT, Levinsohn DG, Harrison MR, Kaban LB: An in utero model of craniosynostosis. J Craniofacial Surg 3:70-8, 1992.

Kuller JA, Yankowitz J, Goldberg JD, Harrison MR, Adzick NS, Filly RA, Callen PW, Golbus MS. Outcome of antenatally diagnosed cystic adenomatoid malformation. Am J Ob Gyn 167:1038-41, 1992.

Longaker MT, Stern M, Lorenz HP, Whitby DJ, Harrison MR, Adzick NS, Kaban LB: A model for fetal cleft lip repair in lambs. Plast Reconstr Surg 90:750-6, 1992.

Estes JM, Whitby DJ, Lorenz HP, Longaker MT, Szabo Z, Adzick NS, Harrison MR: Endoscopic creation and repair of fetal cleft lip. Plast Reconstr Surg 90:743-6, 1992.

Jennings RW, Adzick NS, Longaker MT, Lorenz HP, Estes JM, Harrison MR: New techniques in fetal surgery. J Pediatr Surg 27:1329-33, 1992.

Jennings RW, Flake AW, Massan G, Pellegrini CA, Adzick NS, Harrison MR: A novel endoscopic transgastric fundoplication procedure for gastroesophageal reflux. J Laparoendoscopic Surg 2:207-13, 1992.

Jennings RW, Lorenz HP, Duncan BW, Bradley SM, Harrison MR, Adzick NS: Adult to neonate lung transplantation: Anatomic considerations. J Pediatr Surg 27:1329-33, 1992.

Duncan BW, Eraklis AE, Adzick NS: Retroperitoneal alimentary tract duplications detected in utero. J Pediatr Surg 27:1231-1233, 1992.

Estes JM, MacGillivray TE, Hedrick MH, Adzick NS, Harrison MR: Fetoscopic surgery for treatment of congenital anomalies. J Pediatr Surg 27:950-954, 1992.

Longaker MT, Moelleken BRW, Cheng JC, Jennings RW, Gordon L, Adzick NS, Harrison MR, Simmons D: Fetal fracture healing in a lamb model. Plast Reconst Surg 90:161-171, 1992.

Adzick NS: On the horizon: Neonatal lung transplantation. Arch Dis Child 67:455-7, 1992.

Duncan BW, Howell L, Harrison MR, Adzick NS, deLorimier AA: Tracheostomy in children with emphasis on home care. J Pediatr Surg 27:432-435, 1992.

Duncan BW, Adzick NS, deLorimier AA, Zoger S, Harrison MR: Necrotizing fascitis in children with acute lymphoblastic leukemia. J Pediatr Surg 27:668-671, 1992.

Lorenz HP, Longaker MT, Perchoka LA, Jennings RW, Harrison MR, Adzick NS: Scarless wound repair: A human fetal skin model. Development 114:253-259, 1992.

1991

Adzick NS: A new Wilms' tumor marker. Dialogues in Pediatric Urology 14:6-7, 1991.

Michaels BM, Piscatelli S, Siebert JW, Jennings RW, Longaker MT, Adzick NS: Amniotic fluid stimulates or inhibits fibroblasts, depending on gestational age. Surgical Forum 42:656-658, 1991.

Moelleken BRW, Longaker MT, Cheng JC, Jennings RW, Levinsohn DG, Gordon L, Adzick NS, Harrison MR, Simmons D: Fetal fracture healing in a large animal model. Surgical Forum 42:668-670, 1991.

Longaker MT, Bouhana KS, Roberts AB, Harrison MR, Adzick NS, Banda MJ: Regulation of fetal wound healing. Surgical Forum 42:575-577, 1991.

Jennings RW, Adzick NS, Longaker MT, Lorenz HP, Estes JM, Harrison MR: Fetal intraosseous access: A new approach to accessing the fetal circulation during fetal surgery. Surgical Forum 42:659-661, 1991.

Estes JM, Spencer EM, Longaker MT, Adzick NS: Insulin-like growth factor-II in ovine wound fluid: Developmental regulation. Surgical Forum 42:659-661, 1991.

Crombleholme TM, Shiraishi H, Adzick NS, Langberg J, Silverman N, Harrison MR: A model of non-immune hydrops in fetal lambs: Complete heart block induced hydrops fetalis. Surgical Forum 42:487-489, 1991.

Crombleholme TM, Adzick NS, Hardy K, Longaker MT, Duncan BW, Harrison MR: Pulmonary lobar transplantation in neonatal swine: A model for the treatment of diaphragmatic hernia. Current Surgery 48:148-149, 1991.

Longaker MT, Adzick NS: The biology and therapeutic implications of fetal wound healing. Clinical Materials 8:223-227, 1991.

Rittenberg T, Longaker MT, Adzick NS, Ehrlich HP: Sheep amniotic fluid has a protein factor which stimulates human fibroblast populated collagen lattice contraction. J Cell Physiol 149:444-450, 1991.

Stern M, Longaker MT, Adzick NS, Harrison MR, Stern R: Hyaluronidase in urine of Wilms' tumor patients. J Natl Canc