Aline Rodrigues Hoffmann,
I am a board certified veterinary anatomic pathologist involved and dedicated to research, diagnostic pathology, and training of professional students and veterinary anatomic pathology residents. I am particularly interested and passionate about dermatopathology and fungal diagnostics. I am committed to improvement of animal health and have focused my research career on investigating the role the skin microbiome plays in health and disease in companion animals, pathogenesis of infectious diseases, basic dermatopathology, and microbiology. A special area of my research interest is the development of molecular diagnostics for identification of fungal organisms in formalin fixed paraffin embedded tissues and cytology slides. Through many collaborations, I have supported toxicology studies, in particular investigating the effects of air pollution in animal models.
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About Aline Rodrigues Hoffmann

I am a board certified veterinary anatomic pathologist involved and dedicated to research, diagnostic pathology, and training of professional students and veterinary anatomic pathology residents. I am particularly interested and passionate about dermatopathology and fungal diagnostics. I am committed to improvement of animal health and have focused my research career on investigating the role the skin microbiome plays in health and disease in companion animals, pathogenesis of infectious diseases, basic dermatopathology, and microbiology. A special area of my research interest is the development of molecular diagnostics for identification of fungal organisms in formalin fixed paraffin embedded tissues and cytology slides. Through many collaborations, I have supported toxicology studies, in particular investigating the effects of air pollution in animal models.

Accomplishments

Mid Career Excellence Award for Diagnostics

2023 · American College of Veterinary Pathologists

Clinical Service Award

2015 · Veterinary Medical Teaching Hospital, Texas A&M University

John Paul Delepane Award

2011 · College of Veterinary Medicine & Biomedical Sciences, Texas A&M University

ACVP Young Investigator Award – Experimental disease and Industrial and Toxicology Pathology, 2nd Place “Target cells infected by Cache Valley Virus in the ovine fetus"

2010 · 61st Annual Meeting of The American College of Veterinary Pathologists, Baltimore, MD

Graduate Student Scholarship Award

2009-2010 · College of Veterinary Medicine & Biomedical Sciences, Texas A&M University

L.P. Jones Pathology Resident Award

2009 · College of Veterinary Medicine & Biomedical Sciences, Texas A&M University

ACVP/AAVLD Diagnostic Pathology Travel Award “Central nervous system pathology of naturally ocurring Trypanosoma evansi infection in horses”

2007 · 58th Annual Meeting of The American College of Veterinary Pathologists, Savannah, GA.

Teaching Profile

Courses Taught

2021-2025

VEM5751 Anatomic Path Core Clerkship

2022-2025

VEM5851 Adv. Anatomic Pathology Clerkship

2022-2025

VEM5162 Vet Pathology 2

Board Certifications

Veterinary Anatomic Pathologist

American College of Veterinary Pathologists

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0001-6148-2531

Areas of Interest

Dermatopathology

Environmental Toxicology

Fungal Diagnostics

Skin Microbiome

Publications

2024

Facial and systemic mucormycosis caused by Lichtheimia corymbifera in a goat: case report and literature review of fungal infections in goats.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 36(3):463-467 [DOI] 10.1177/10406387241236751. [PMID] 38465904.

2024

Telangiectatic osteosarcoma in four dogs: Cytologic, histopathologic, cytochemical, and immunohistochemical findings.

Veterinary clinical pathology. 53(1):85-92 [DOI] 10.1111/vcp.13338. [PMID] 38418390.

2023

Case report: Intraneural perineurioma in dogs: a case series and brief literature review.

Frontiers in veterinary science. 10 [DOI] 10.3389/fvets.2023.1233230. [PMID] 38274660.

2023

Common superficial and deep cutaneous bacterial infections in domestic animals: A review

Veterinary Pathology. 60(6):796-811 [DOI] 10.1177/03009858231176558.

2023

Cutaneous phaeohyphomycosis in a greater bulldog bat (Noctilio leporinus) in northeastern Brazil.

Journal of comparative pathology. 201:37-40 [DOI] 10.1016/j.jcpa.2022.12.013. [PMID] 36701871.

2023

Hyphae, pseudohyphae, yeasts, spherules, spores, and more: A review on the morphology and pathology of fungal and oomycete infections in the skin of domestic animals

Veterinary Pathology. 60(6):812-828 [DOI] 10.1177/03009858231173715.

2023

Paraconiothyrium cyclothyrioides, a novel cutaneous fungal pathogen in a dog and a cat.

Veterinary dermatology. 34(4):363-366 [DOI] 10.1111/vde.13155. [PMID] 36919229.

2023

Skin biopsy guidelines: tips and advice from veterinary pathologists to practitioners.

Journal of the American Veterinary Medical Association. 261(S1):S114-S121 [DOI] 10.2460/javma.22.12.0586. [PMID] 37037420.

2023

The feline skin microbiome: interrelationship between health and disease.

Journal of feline medicine and surgery. 25(7) [DOI] 10.1177/1098612X231180231. [PMID] 37404049.

2023

Tolerability and the effect on skin Staphylococcus pseudintermedius density of repeated diluted sodium hypochlorite (bleach) baths at 0.005% in healthy dogs.

Veterinary dermatology. 34(6):489-494 [DOI] 10.1111/vde.13186. [PMID] 37357372.

2022

Talaromyces spp. infections in dogs from the Southern United States

Veterinary Pathology. 59(3):451-454 [DOI] 10.1177/03009858221075589.

2022

An ancient haplotype containing antimicrobial peptide gene variants is associated with severe fungal skin disease in Persian cats

PLOS Genetics. 18(2) [DOI] 10.1371/journal.pgen.1010062. [PMID] 35157719.

2022

Immunophenotype of the inflammatory response in the central and enteric nervous systems of cockatiels (Nymphicus hollandicus) experimentally infected with parrot bornavirus 2

Veterinary Pathology. 59(3):493-497 [DOI] 10.1177/03009858211069166.

2021

Characterization of staphylococcal communities on healthy and allergic feline skin

Veterinary Dermatology. 32(1) [DOI] 10.1111/vde.12885.

2021

Characterization of the cutaneous mycobiota in Persian cats with severe dermatophytosis

Veterinary Dermatology. 32(4) [DOI] 10.1111/vde.12969. [PMID] 34033174.

2021

Diagnostic Accuracy of a Direct Panfungal Polymerase Chain Reaction Assay Performed on Stained Cytology Slides

Veterinary Pathology. 58(3):542-548 [DOI] 10.1177/0300985821991562.

2021

Pyogranulomatous panniculitis in a domestic cat associated with Pseudomonas luteola infection

Veterinary Dermatology. 32(1) [DOI] 10.1111/vde.12893.

2020

Characterization of Cutaneous Bacterial Microbiota from Superficial Pyoderma Forms in Atopic Dogs.

Pathogens (Basel, Switzerland). 9(8) [DOI] 10.3390/pathogens9080638. [PMID] 32781634.

2020

Immersion Foot Syndrome in 6 Equids Exposed to Hurricane Floodwaters

Veterinary Pathology. 57(2):290-295 [DOI] 10.1177/0300985819900019.

2020

Retrospective Analysis of Aetiological Agents Associated with Pulmonary Mycosis Secondary to Enteric Salmonellosis in Six Horses by Panfungal Polymerase Chain Reaction.

Journal of comparative pathology. 174:1-7 [DOI] 10.1016/j.jcpa.2019.10.002. [PMID] 31955794.

2019

Correlating Gastrointestinal Histopathologic Changes to Clinical Disease Activity in Dogs With Idiopathic Inflammatory Bowel Disease

Veterinary Pathology. 56(3):435-443 [DOI] 10.1177/0300985818813090.

2019

Distribution of Viral Antigen and Inflammatory Lesions in the Central Nervous System of Cockatiels (Nymphicus hollandicus) Experimentally Infected with Parrot Bornavirus 2

Veterinary Pathology. 56(1):106-117 [DOI] 10.1177/0300985818798112.

2019

Histoplasmosis and multicentric lymphoma in a Nubian goat.

Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc. 31(5):770-773 [DOI] 10.1177/1040638719868810. [PMID] 31378198.

2019

The feline cutaneous and oral microbiota are influenced by breed and environment.

PloS one. 14(7) [DOI] 10.1371/journal.pone.0220463. [PMID] 31361788.

2018

Novel association of Psychrobacter and Pseudomonas with malodour in bloodhound dogs, and the effects of a topical product composed of essential oils and plant‐derived essential fatty acids in a randomized, blinded, placebo‐controlled study

Veterinary Dermatology. 29(6) [DOI] 10.1111/vde.12689.

2018

Pulmonary and systemic fungal infections in an Atlantic spotted dolphin and a Bryde’s whale, Brazil.

Diseases of aquatic organisms. 128(1):73-79 [DOI] 10.3354/dao03207. [PMID] 29565255.

2017

Are anti-ganglioside antibodies associated with proventricular dilatation disease in birds?

PeerJ. 5 [DOI] 10.7717/peerj.3144. [PMID] 28413724.

2017

Atypical cutaneous cryptococcosis in four cats in the USA.

Veterinary dermatology. 28(4):405-e97 [DOI] 10.1111/vde.12423. [PMID] 28133852.

2017

Characterization of the cutaneous mycobiota in healthy and allergic cats using next generation sequencing.

Veterinary dermatology. 28(1):71-e17 [DOI] 10.1111/vde.12373. [PMID] 27553477.

2017

Interobserver Agreement Using Histological Scoring of the Canine Liver.

Journal of veterinary internal medicine. 31(3):778-783 [DOI] 10.1111/jvim.14684. [PMID] 28295598.

2017

Nano-curcumin safely prevents streptozotocin-induced inflammation and apoptosis in pancreatic beta cells for effective management of Type 1 diabetes mellitus.

British journal of pharmacology. 174(13):2074-2084 [DOI] 10.1111/bph.13816. [PMID] 28409821.

2017

The cutaneous ecosystem: the roles of the skin microbiome in health and its association with inflammatory skin conditions in humans and animals.

Veterinary dermatology. 28(1):60-e15 [DOI] 10.1111/vde.12408. [PMID] 28133874.

2017

The feline skin microbiota: The bacteria inhabiting the skin of healthy and allergic cats.

PloS one. 12(6) [DOI] 10.1371/journal.pone.0178555. [PMID] 28575016.

2016

Canine and Human Atopic Dermatitis: Two Faces of the Same Host-Microbe Interaction.

The Journal of investigative dermatology. 136(6):1087-1089 [DOI] 10.1016/j.jid.2016.03.015. [PMID] 27212648.

2016

Serum C-reactive protein and S100A12 concentrations in dogs with hepatic disease.

The Journal of small animal practice. 57(9):459-64 [DOI] 10.1111/jsap.12504. [PMID] 27271454.

2016

The Microbiome: The Trillions of Microorganisms That Maintain Health and Cause Disease in Humans and Companion Animals.

Veterinary pathology. 53(1):10-21 [DOI] 10.1177/0300985815595517. [PMID] 26220947.

2015

What is living on your dog’s skin? Characterization of the canine cutaneous mycobiota and fungal dysbiosis in canine allergic dermatitis.

FEMS microbiology ecology. 91(12) [DOI] 10.1093/femsec/fiv139. [PMID] 26542075.

2014

Immunization with a Borrelia burgdorferi BB0172-derived peptide protects mice against lyme disease.

PloS one. 9(2) [DOI] 10.1371/journal.pone.0088245. [PMID] 24505447.

2014

Immunohistochemical expression of ionized calcium binding adapter molecule 1 in cutaneous histiocytic proliferative, neoplastic and inflammatory disorders of dogs and cats.

Journal of comparative pathology. 151(4):347-51 [DOI] 10.1016/j.jcpa.2014.07.003. [PMID] 25172051.

2014

The skin microbiome in healthy and allergic dogs.

PloS one. 9(1) [DOI] 10.1371/journal.pone.0083197. [PMID] 24421875.

2013

Ovine fetal immune response to Cache Valley virus infection.

Journal of virology. 87(10):5586-92 [DOI] 10.1128/JVI.01821-12. [PMID] 23468505.

2012

Identification of the target cells and sequence of infection during experimental infection of ovine fetuses with Cache Valley virus.

Journal of virology. 86(9):4793-800 [DOI] 10.1128/JVI.06858-11. [PMID] 22379096.

Grants

Education

PhD

2011 · Texas A&M University

Residency in Anatomic Pathology

2009 · Texas A&M University

Master of Science

2006 · Universidade Federal de Santa Maria (Brazil)

Veterinary Medicine

2004 · Universidade Federal de Santa Maria (Brazil)